Results 11 to 20 of about 93,913 (298)

Biomimetic macrophage membrane-coated gold-quantum dots with tumor microenvironment stimuli-responsive capability for tumor theranostic

Materials Today Bio, 2022
Tumor microenvironment (TME) is intently related to tumor growth, progression and invasion, leading to drug resistance and insufficient therapeutic efficacy.
Fan Wang, Qinghua Yu, Jia Li, Junhao Jiang, Tao Deng, Chao Yu   +5 more
doaj   +1 more source

Synthesis and spectral characteristics of N-(1-([1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylamino)-2,2,2-trichloroethyl)carboxamides

Heterocyclic Communications, 2019
Based on readily available N-(2,2,2-trichloro-1-hydroxyethyl)carboxamides, N-(2,2,2-trichloro-1-(3-(3-mercapto-4H-1,2,4-triazol-4-yl)thioureido)ethyl) carboxamides, dehydrosulfurization–under the influence of excess HgO–led to the formation of N-(1-([1,2,
Zadorozhnii Pavlo V., Pokotylo Ihor O., Kiselev Vadym V., Kharchenko Aleksandr V., Okhtina Oxana V.   +4 more
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Syntheses, crystal structure, thermal behavior, and anti-tumor activity of three ternary metal complexes with 2-chloro-5-nitrobenzoic acid and heterocyclic compounds

Heterocyclic Communications, 2022
Three complexes, namely complex (1), complex (2), and complex (3), were synthesized and characterized by X-ray diffraction, thermogravimetric study, and elemental study.
Zhang Zhongyu, Chen Meng, Tong Mingqiong, Sun Wan, Dong Pingxuan, Song Xinfeng, Wang Xiaoyue   +6 more
doaj   +1 more source

A novel mRNA vaccine, SYS6006, against SARS-CoV-2

Frontiers in Immunology, 2023
The development of vaccines that can efficiently prevent the infection of SARS-CoV-2 is necessary to fight the COVID-19 epidemic. mRNA vaccine has been proven to induce strong humoral and cellular immunity against SARS-CoV-2.
Ke Xu, Wenwen Lei, Bin Kang, Bin Kang, Hanyu Yang, Hanyu Yang, Yajuan Wang, Yajuan Wang, Yanli Lu, Yanli Lu, Lu Lv, Lu Lv, Yufei Sun, Yufei Sun, Jing Zhang, Xiaolin Wang, Xiaolin Wang, Mengjie Yang, Mo Dan, Mo Dan, Guizhen Wu   +20 more
doaj   +1 more source

Genetic Polymorphisms of Long Non-coding RNA Linc00312 Are Associated With Susceptibility and Predict Poor Survival of Nasopharyngeal Carcinoma

Frontiers in Cell and Developmental Biology, 2021
BackgroundLinc00312 is dysregulated in nasopharyngeal carcinoma (NPC) and participates in the initiation and progression of NPC. Our previous studies suggested that linc00312 was able to enhance the sensitivity of NPC cells to irradiation and NPC ...
Zhen Guo, Zhen Guo, Mei-Hua Bao, Mei-Hua Bao, Yun-Xia Fan, Yun-Xia Fan, Yan Zhang, Yan Zhang, Hai-Yan Liu, Hai-Yan Liu, Xiao-Long Zhou, Xiao-Long Zhou, Ben Wu, Ben Wu, Qing-Qing Lu, Bin-Sheng He, Bin-Sheng He, Xu-Ying Nan, Xu-Ying Nan, Jiao-Yang Lu, Jiao-Yang Lu   +20 more
doaj   +1 more source

Crystal structure of (1,10-phenanthroline-κ2N,N′)-bis(3-thiophenecarboxylato-κ2O,O′)copper(II), C22H14N2O4S2Cu

Zeitschrift für Kristallographie - New Crystal Structures, 2021
C22H14N2O4S2Cu, orthorhombic, Pbcn (no. 60), a = 20.171(7) Å, b = 9.684(3) Å, c = 10.372(4) Å, V = 2025.9(12) Å3, Z = 4, Rgt(F) = 0.0334, wRref(F2) = 0.0908, T = 273.15 K.
Zhang Zhongyu, Men Xiaoxia, Han Bing, Sun Chunyan   +3 more
doaj   +1 more source

Nanomedicine potentiates mild photothermal therapy for tumor ablation

Asian Journal of Pharmaceutical Sciences, 2021
The booming photothermal therapy (PTT) has achieved great progress in non-invasive oncotherapy, and paves a novel way for clinical oncotherapy. Of note, mild temperature PTT (mPTT) of 42–45 °C could avoid treatment bottleneck of the traditional PTT ...
Zijun Jiang, Tianyi Li, Hao Cheng, Feng Zhang, Xiaoyu Yang, Shihao Wang, Jianping Zhou, Yang Ding   +7 more
doaj   +1 more source

STABILITY OF PHARMACEUTICAL PREPARATIONS

MINAR International Journal of Applied Sciences and Technology, 2022
Pharmaceutical product must be chemically, physically and therapeutically stable to ensure the health and preventive aspect. We have to study the effect of many factors on drug formulation as well as packaging and storage. Stability of pharmaceutical preparation act as the identity card of the drug to reach the pharmacy, the hospital, and the consumer ...
Hana Sh. MAHMOOD, Nada A. KHALIL, Ahlam A.SHEHAB   +2 more
openaire   +1 more source

Effectiveness and safety of rivaroxaban or low-molecular-weight heparin in non-major orthopedic surgery: a meta-analysis of randomized controlled trials

Journal of Orthopaedic Surgery and Research
Background Patients undergoing non-major orthopedic surgery often face an increased risk of venous thromboembolism due to the necessity of immobilization postoperatively. Current guidelines commonly recommend the use of low-molecular-weight heparin (LMWH)
Lemei Zhu, Bohua Zhu, Pingping Bing, Mingxu Qi, Binsheng He   +4 more
doaj   +1 more source

Fabricating Oral Disintegrating Tablets Without Disintegrant Using Powder-Based 3D Printing

Pharmaceutics
Background: Powder-based 3D printing, an advanced additive manufacturing technique, can produce oral disintegrating tablets (ODTs) without disintegrants, creating larger-pored tablets via layer-by-layer powder stacking for better water absorption than ...
Jiu Wang, Shunfang Liu, Minmei Lin, Peihong Chen, Huagui Yi, Zhufen Lv, Yuanfen Liu   +6 more
doaj   +1 more source