Results 131 to 140 of about 165,068 (304)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

The life expectancy gains from pharmaceutical drugs: a critical appraisal of the literature [PDF]

open access: yes
Several studies suggest that, on the basis of life expectancy (LE) regressions, new pharmaceutical drugs are responsible for some of the marked gains in LE observed over the last 50 years. We critically appraise these studies.
Paul Grootendorst   +2 more
core  

Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues

open access: yesAdvanced Science, EarlyView.
Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak   +6 more
wiley   +1 more source

Pharmaceutical Services [PDF]

open access: yesChemical & Engineering News Archive, 2002
openaire   +1 more source

PHARMACEUTICAL SERVICES IN PHARMACIES : RESEARCH IN THE BANJARBARU AREA

open access: yes, 2020
Pharmaceutical services activity at pharmacies should implement the Government standard. The aim of this study was to measure the quality of pharmaceutical services.
Kartinah, Nani
core  

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

Montelukast and Delirium Risk During Intensive Care Unit (ICU) Stay: Findings from a Cohort Study

open access: yesClinical Pharmacology: Advances and Applications
Alaa Almagthali,1 Khalid Al Sulaiman,2– 6 Samiah Alsohimi,7 Kholoud Al Aamer,2,8 Alaa Naser Kurdi,9,10 Alwaleed Nasser Al Qurashi,11 Nawaf Shalih Alqahtani,2 Aljoharah Khaled Alqub,2 Waad A Alnami,12 Abdullah M Alhammad,13 Fatimah Abudayah,14 Ohoud ...
Almagthali A   +11 more
doaj  

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