Results 151 to 160 of about 4,638,728 (306)

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

open access: yesAdvanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao   +12 more
wiley   +1 more source

European Pharmaceutical Price Regulation, Firm Profitability, and R&D Spending [PDF]

open access: yes
EU countries closely regulate pharmaceutical prices whereas the U.S. does not. This paper shows how price constraints affect the profitability, stock returns, and R&D spending of EU and U.S. firms. Compared to EU firms, U.S.
John A. Vernon, Joseph H. Golec
core  

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

open access: yesAdvanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho   +13 more
wiley   +1 more source

Mapping of rural health-care services

open access: yes, 2010
Objective. The availability of health services in rural areas creates challenges for the existing providers and health consumers. In preparation for an exploratory study of these issues, we aimed to identify 1) a suitable community to study, and 2) the ...
Emmerton, Lynne   +4 more
core  

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

open access: yesAdvanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta   +6 more
wiley   +1 more source

MS

open access: yes, 2007
thesisThe Social Security Amendments of 1965 have created new opportunities and challenges of members of the health team to provide their professional services.
Matsumura, Keiji Kay
core  

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