Results 201 to 210 of about 6,007,608 (352)

Association between hospital size and quality improvement for pharmaceutical services [PDF]

open access: bronze, 2004
David P. Nau   +3 more
openalex   +1 more source

HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim   +9 more
wiley   +1 more source

Secondary Electron Hyperspectral Imaging of Carbons: New Insights and Good Practice Guide

open access: yesAdvanced Science, EarlyView.
Secondary hyperspectral imaging of carbon surfaces is assessed with reference materials and in comparison to standard spectroscopies. Characterization of functional carbon materials from battery research reveals otherwise inaccessible information about the distribution of sp2 and amorphous carbon, as shown in graphite anode and carbon coated lithium ...
James F. Nohl   +22 more
wiley   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen   +11 more
wiley   +1 more source

Pharmaceutical Care by Clinical Pharmacy Service of the Pharmacist in the Palliative Care Unit. Survey for Improving the Flavoring of Morphine Oral Solution.

open access: bronze, 2000
KENICHI KONISHI   +6 more
openalex   +2 more sources

Water‐Catalytic Deconstructive and Proton Transfer Cyclopropanation of Sulfoxonium Ylide with Olefin

open access: yesAdvanced Science, EarlyView.
Water‐catalytic deconstructive and proton transfer cyclopropanation of sulfoxonium ylide with olefin is developed through a sequential water‐mediated ring‐closing/opening reaction. This atom‐economical, environmentally friendly methodology offers easy access to a range of cyclopropyl ketones with moderate to good yields.
Xianglin Yu   +4 more
wiley   +1 more source

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