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Metaheuristic approach for solving the vehicle routing problem: Application in pharmaceutical society

2013 International Conference on Control, Decision and Information Technologies (CoDIT), 2013
In this paper, we address the capacitated vehicle routing problem CVRP. This problem consists to optimize the itineraries of the vehicles that must do with a minimum cost and it by the use of a fleet homogeneous while respecting the constraints of time, volume and capacity However, the techniques giving the optimal path are relatively gluttonous in ...
Smaili Yamina   +2 more
openaire   +1 more source

Cargo theft weighted vehicle routing problem: modeling and application to the pharmaceutical distribution sector

Soft Computing, 2018
We present a variant of the weighted vehicle routing problem to design distribution routes in high theft risk areas. The model aims to minimize transportation and cargo theft costs. It uses a set of flow decision variables to calculate cargo value in each edge.
Hugo M. Repolho   +3 more
openaire   +1 more source

Next-generation pharmaceutically acceptable vehicles for eye drops (preliminary report)

Russian Annals of Ophthalmology
Efficient delivery of instilled drugs into the corneal stroma and intraocular tissues remains a major challenge in ophthalmic pharmacology. Existing enhancers of transmucosal and transepithelial permeability are often toxic and fail to overcome ocular surface barriers effectively.
M.V. Kravchik   +11 more
openaire   +1 more source

Syrup of cranberry, a new pharmaceutical vehicle

Journal of the American Pharmaceutical Association (Scientific ed.), 1940
J.A. Lubitz, C.R. Fellers, J.A. Clague
openaire   +1 more source

Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL.

Cancer research, 1996
Studies in humans and mice have demonstrated a nonlinear pharmacokinetic behavior of paclitaxel. Because of its poor water solubility, the drug is formulated in a mixture of Cremophor EL and ethanol (1:1, v/v; Taxol). We hypothesized that the substantial amounts of concurrently administered Cremophor EL on the disposition of paclitaxel, female FVB mice
Sparreboom, A.   +3 more
openaire   +2 more sources

Pharmaceutical drug delivery systems and vehicles

2018
Suryakant Swain   +2 more
openaire   +1 more source

4889845 Vehicle for topical application of pharmaceuticals

General Pharmacology: The Vascular System, 1990
openaire   +1 more source

An update on cyclodextrins as drug vehicles for antimicrobial applications

Journal of Pharmaceutical Technolgy, 2020
Ece Ozcan Bulbul   +2 more
exaly  

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