Results 41 to 50 of about 70,716 (268)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Jurisprudent Pharmacy as a New Pharmacy−Feedback from Litigation to Pharmacy−
YAKUGAKU ZASSHI, 2003 Risk management in the medical field is said to be entering into the third generation. By definition, the first generation covers the period until some 10 years ago when medical errors themselves used to be regarded as inconceivable and therefore as something of a taboo.
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sovremennye Issledovaniâ Socialʹnyh Problem, 2015 В настоящее время, при оценке эффективности аптечных учреждений не учитывается ее социальный результат. Анализ деятельности аптек и их принадлежность к системе здравоохранения позволили считать необходимым предложение методики определения социальной ...
Michael Evgenevich Volchanskiy +3 more
doaj +1 more source
Analysis of the current state and problems of pharmacy production of medicines in UKRAINE
Фармацевтичний журнал, 2020 The current state of providing of the population of Ukraine with extemporaneous drugs produced in pharmacies is one of the most acute social problems of the healthcare system and pharmacy.
A. S. Nemchenko +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Exploratory Research in Clinical and Social PharmacyBackground: Medication reconciliation and -reviews are not emphasized in the pharmacy curriculums in Norway and graduated pharmacists are at novice level.
Marianne Lea +3 more
doaj +1 more source
Implementing pharmacy-located HPV vaccination: findings from pilot projects in five U.S. states
Human Vaccines & Immunotherapeutics, 2019 Pharmacies are promising alternative settings for human papillomavirus (HPV) vaccination because of their population reach, convenience, and existing infrastructure for vaccine delivery.
William A. Calo +6 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source