Results 101 to 110 of about 115,679 (313)
Introduction: Communication between health professionals (HP) is a key issue to enhance quality and efficiency of health care system. (1,2). Community pharmacists (CPs) are often not integrated in the current HP communication model.
Ainhoa Oñatibia-Astibia +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Pharmacist-led medication reviews for older care home residents: achieving a person-centred approach
Background: Clinical pharmacists in England are responsible for undertaking Structured Medication Reviews (SMRs). Guidance state these should be person-centred and holistic, however there is no universally accepted definition or model of person-centred ...
Rachel J. Lewis (21359284)
core +1 more source
A Smart mobile health intervention: Improving hypertension self-management through whatsapp-delivered video education [PDF]
Hypertension remains a leading global health challenge, particularly in low-resource settings where access to health education is limited. This study aimed to evaluate the effectiveness of a video-based educational intervention delivered via WhatsApp in ...
Akhyar Zeda Kumala +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Objective: This study aims to characterize the breast cancer (BC) patient journey in Rio Grande do Sul (RS), Brazil, through the perspectives of the High Complexity Oncology Assistance Centers (CACONs) and High Complexity Oncology Assistance Units ...
Fernando Anschau +7 more
doaj +1 more source
The potential influence of estrogen-containing oral contraception on clozapine metabolism in a patient with known pharmacogenomic status [PDF]
Clozapine is primarily metabolized via cytochrome P450(CYP)1A2 and to a lesser extent CYP3A4, CYP2C19, and CYP2D6. Metabolic inhibitors of clozapine, such as fluvoxamine and ciprofloxacin, are important to recognize to avoid adverse drug events. Estrogen-
Alyssa K. Kuhn +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Pharmacist-led lipid clinic for surgical patients with peripheral vascular disease
Pharmacist-led lipid clinic for surgical patients with peripheral vascular ...
R Fyfe (13415811) +3 more
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