RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Impact of pharmacist-led deprescribing interventions on medication related outcomes among older adults: a systematic review and meta-analysis. [PDF]
Tesfaye ZT, Horsa BA, Yismaw MB.
europepmc +1 more source
Values and Value Dilemmas in Pharmacology: A Theological Perspective [PDF]
Maestri, William F.
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Patient satisfaction with pharmaceutical services in the context of chief pharmacist system: a comparative study from Shaanxi Province, China. [PDF]
Xu Y +10 more
europepmc +1 more source
Feasibility and impact of pharmacist-led penicillin allergy delabelling using the PEN-FAST scoring tool in a Canadian tertiary care hospital. [PDF]
Kamaliddin C +4 more
europepmc +1 more source
Parenteral Nutrition Management from the Clinical Pharmacy Perspective: Insights and Recommendations from the Saudi Society of Clinical Pharmacy. [PDF]
Albanyan N +6 more
europepmc +1 more source
The contribution of community pharmacy to improving the public’s health: summary report of the literature review 1990–2007 [PDF]
Anderson, Claire +2 more
core +1 more source
The impact of pharmacist-led medication therapy management on the efficacy of cancer pain control: a pre-post interventional study. [PDF]
Dong Y, Liu Y, Zheng S, Feng L.
europepmc +1 more source

