Results 51 to 60 of about 263,791 (359)

Preparation and Evaluation of Telmisartan Solid Dispersion as Sublingual Tablets

مجلة كلية الطب
Background: Telmisartan is an antihypertensive angiotensin II receptor antagonist drug commonly used to treat hypertension and renal disease. Based on the Biopharmaceutical Classification System.  It’s a Class II poorly soluble drug.
Hiba Ayad Aziz, Entidhar J. Al-Akkam
doaj   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

FEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic, Morana Dulic, Ita Gruic‐Sovulj   +2 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Intranasal naloxone to treat suspected synthetic cannabinoid overdose: A case report and literature review [PDF]

Mental Health Clinician
Synthetic cannabinoids (SCs), such as K2 or spice, are potent, intoxicating, laboratory-produced compounds designed to mimic Δ9-tetrahydrocannabinol (Δ9-THC).
Jaden Dickinson, PharmD, BCPP, Tiffany Buckley, PharmD, BCPP, BCPS   +1 more
doaj   +1 more source

Pharmacogenomic testing and its future in community pharmacy [PDF]

, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

The pharmacist and the EHR [PDF]

Journal of the American Medical Informatics Association, 2016
The adoption of electronic health records (EHRs) across the United States has impacted the methods by which health care professionals care for their patients. It is not always recognized, however, that pharmacists also actively use advanced functionality within the EHR.
Charlene R. Weir, John Poikonen, Scott D. Nelson, David El Halta, Thomas J. Reese   +4 more
openaire   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Learning to prescribe - pharmacists' experiences of supplementary prescribing training in England [PDF]

, 2008
Background: The introduction of non-medical prescribing for professions such as pharmacy and nursing in recent years offers additional responsibilities and opportunities but attendant training issues.
A Elston, Allen Hutchinson, Anthony Avery, Centre for the Advancement of Inter-professional Education (CAIPE), Claire Anderson, D Dawoud, D Silverman, Department of Health, Department of Health, E Bradley, Elizabeth Murphy, F Lloyd, J George, Joanne Lymn, Julie Ratcliffe, L Emmerton, Louise Guillaume, M Offredy, M Tully, P Black, P Buckley, Paul Bissell, Paul Ward, R Jones, Richard J Cooper, RJ Cooper, RJ Cooper, Royal Pharmaceutical Society of Great Britain, Royal Pharmaceutical Society of Great Britain, S Morrison-Griffiths, S Warchal   +30 more
core   +8 more sources

WHY NOT THE PHARMACISTS? [PDF]

Journal of the American Medical Association, 1887
Dear Sir: —The late innovation of having a Section of Dentistry at the Ninth International Medical Congress working so well, and the great excellence of the pharmaceutical display, invite the question, Why not have a Section of Pharmacy in the American Medical Association? It is simply raised for discussion, adding the following memoranda: Pharmacy
openaire   +2 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source