Results 231 to 240 of about 303,672 (340)

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Pharmacist substitution of slow-release theophylline products

open access: bronze, 1989
David Sly   +9 more
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Pharmacists' knowledge, attitudes, and practices toward preventing congenital disabilities: a cross sectional study in Saudi Arabia. [PDF]

open access: yesBMC Health Serv Res
Alshehri FS   +10 more
europepmc   +1 more source

ANOTHER LOOK AT THE PHARMACIST AS AN ADVISER

open access: gold, 1985
Michele Dullinger, Albert I. Wertheimer
openalex   +1 more source

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