Results 61 to 70 of about 349,309 (294)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

A new prescription for empirical ethics research in pharmacy: a critical review of the literature [PDF]

open access: yes, 2007
Empirical ethics research is increasingly valued in bioethics and healthcare more generally, but there remain as yet under-researched areas such as pharmacy, despite the increasingly visible attempts by the profession to embrace additional roles beyond ...
Bissell, P., Cooper, R.J., Wingfield, J.
core   +2 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Antimicrobial dispensing practices and determinants of antimicrobial resistance: a qualitative study among community pharmacists in Pakistan

open access: yesFamily Medicine and Community Health Journal, 2019
Background There are concerns with the extent of dispensing of antibiotics among community pharmacists in Pakistan often without a prescription adding to antimicrobial resistance (AMR) rates.
Z. Saleem   +4 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Practical Strategies for Pharmacist Integration with Primary Care: A Workbook. [PDF]

open access: yes, 2014
This workbook is a practical set of tips and resources to assist pharmacists in providing clinical pharmacy services to primary care providers and their patients.
Biddle, Michael A, Kennedy, Amanda G
core   +1 more source

Dementia: What pharmacists need to know.

open access: yesCanadian Pharmacists Journal / Revue des Pharmaciens du Canada, 2017
En tant que professionnels des soins primaires qui voient régulièrement des patients, les pharmaciens sont à même de reconnaître les premiers signes de démence et d’encourager les patients à recevoir une évaluation.
S. Duong, Tejal Patel, Feng Chang
semanticscholar   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

The impact of a post-take ward round pharmacist on the risk score and enactment of medication-related recommendations [PDF]

open access: yes, 2020
There is a scarcity of published research describing the impact of a pharmacist on the post-take ward round (PTWR) in addition to ward-based pharmacy services. The aim of this paper was to evaluate the impact of clinical pharmacists' participation on the
Bullock, Brooke   +4 more
core   +1 more source

Pharmacists’ Attitudes toward Dispensing Naloxone and Medications for Opioid Use Disorder: A Scoping Review of the Literature

open access: yesSubstance Abuse, 2019
Background Pharmacists are on the frontline caring for patients at risk of an opioid overdose and for patients with an opioid use disorder (OUD). Dispensing naloxone and medications for OUD and counseling patients about these medications are ways ...
A. Muzyk   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy