Results 81 to 90 of about 186,636 (307)
Фармацевтичний журнал, 2018 The role of the pharmacists in providing information on cases of adverse reactions (ARs) and/or lack of effectiveness of drugs in the Pharmacovigilance (PhV) Department of Ukraine is very important.
O. Ya. Mishchenko +2 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
2016 National Survey of Community-Based Pharmacists: Use of Digital Health Technology in Practice
, 2019 The 2016 National Survey of Community-Based Pharmacists: Use of Digital Health Technology in Practice dataset includes the positive impact that the use of digital health is having on Canadian pharmacists’ changing practice needs and on patient safety and
Canadian Pharmacists Association +1 more
core +1 more source
The role of community pharmacists as advisors on prescription medication [PDF]
, 1995 This thesis describes the historical and functional evolution of British community pharmacists showing the succession of a compounding role by a supply function with incumbent bureaucracy.
Gerrett, David
core +1 more source
BMJ OpenBackground Pharmacists are vital to the multidisciplinary care for transplant patients, but the workforce of their work in China remains unclear.Objective To assess the current status of transplant pharmacists' work in China through a national workforce ...
Xin Yu +11 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The role of pharmacists in managing conditions like hypertension: The case of Northern Cyprus
Hypertension is a high-risk factor for cardiovascular diseases and its prevalence rate is increasing due to risk factors such as unhealthy lifestyles and aging populations.
Pinar Taghizadeh
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source