Results 111 to 120 of about 93,887 (308)
, 2015 Huali Wu,1 Jeffrey R Infante,2 Vicki L Keedy,3 Suzanne F Jones,2 Emily Chan,3 Johanna C Bendell,2 Wooin Lee,4 Whitney P Kirschbrown,1 Beth A Zamboni,5 Satoshi Ikeda,6 Hiroshi Kodaira,6 Mace L Rothenberg,3 Howard A Burris III,2 William C Zamboni1,7&ndash ...
Kirschbrown WP +13 more
core
The Dynamics of Neurofilament Light Chain in Spinal Muscular Atrophy
Annals of Neurology, EarlyView.Objective Newborn screening (NBS) for spinal muscular atrophy (SMA) facilitates early diagnosis and treatment for affected individuals. However, fluid biomarkers that provide early insights into disease activity and outcomes in a neonatal cohort and those unable to access (due to reimbursement criteria) or deferring immediate treatment are lacking ...
Arlene D'Silva +13 more
wiley +1 more source
Estimated parameters for pharmacokinetics and pharmacodynamics of rEpo.
, 2018 Estimated parameters for pharmacokinetics and pharmacodynamics of rEpo.
Joydeep Sarkar (592406) +2 more
core +1 more source
Fluids and Barriers of the CNSBackground Oxycodone, a widely used opioid analgesic, has an unbound brain-to-plasma concentration ratio (Kp,uu) greater than unity, indicating active uptake across brain barriers associated with the putative proton-coupled organic cation (H+/OC ...
Frida Bällgren +2 more
doaj +1 more source
Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood
Advanced NanoBiomed Research, EarlyView.Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus +5 more
wiley +1 more source
Active CNS delivery of oxycodone in healthy and endotoxemic pigs
Fluids and Barriers of the CNSBackground The primary objective of this study was to advance our understanding of active drug uptake at brain barriers in higher species than rodents, by examining oxycodone brain concentrations in pigs.
Frida Bällgren +7 more
doaj +1 more source
MoleculesGangliosides are sialic acid-containing glycosphingolipids that play an essential role in many biological and pathophysiological processes. They are present in high amounts in the central nervous system and their abnormal metabolism or expression has ...
Katinka Tarnóczi +3 more
doaj +1 more source
Individualized immunosuppression in transplant patients: potential role of pharmacogenetics.
, 2012 The immunosuppressive drugs used to prevent the rejection of transplanted organs have a narrow therapeutic index. Under treatment results in episodes of rejection leading to either damage or loss of the organ. Over immunosuppression increases the risk of
MacPhee IA +3 more
core +1 more source
Molecular pharmacodynamics of meropenem for nosocomial pneumonia caused by Pseudomonas aeruginosa
mBioHospital-acquired pneumonia (HAP) is a leading cause of morbidity and mortality, commonly caused by Pseudomonas aeruginosa. Meropenem is a commonly used therapeutic agent, although emergent resistance occurs during treatment.
Nicola Farrington +10 more
doaj +1 more source
Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope
Animal Research and One Health, EarlyView.FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad +7 more
wiley +1 more source