Results 241 to 250 of about 181,985 (340)

Dose finding in early-phase human immunodeficiency virus type 1 prevention monoclonal antibody clinical trials. [PDF]

Clin Trials
Huang Y, Zhang B, Zhang L, Mayer BT, Martin T, Hahn W, Hyrien O, Gelderblom HC.   +7 more
europepmc   +1 more source

Pharmacokinetics and Pharmacodynamics of Gallamine Triethiodide in Patients with Total Biliary Obstruction

, 1981
Iqbal Ramzan, C. A. Shanks, E. J. Triggs
openalex   +1 more source

Poly(ethylene Glycol)‐Based Peptidomimetics (Pegtides) of Antimicrobial Peptides

ChemBioChem, EarlyView.
Polyethylene glycol (PEG) is commonly used to improve the pharmacokinetics and pharmacodynamics of therapeutic candidates by conjugation. Here PEG is exploited for peptidomimetic conversion of antimicrobial peptides (AMPs), as candidate antibacterial agents, by replacing their polyamide backbone. The pegtides obtained thereby can be readily synthesized
Conor Shine, John R. F. B. Connolly, Robert D. Murphy, Hazel Lafferty, Abdalmalek Alfnikh, Ned P. Buijs, Hawraa Shahrour, Nathaniel I. Martin, Eoghan O'Neill, George Amarandei, Jimmy Muldoon, Marc Maresca, Deirdre Fitzgerald‐Hughes, Marc Devocelle   +13 more
wiley   +1 more source

Correction to "Results From a Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of ANX005, a C1q Inhibitor, in Patients With Guillain-Barré Syndrome". [PDF]

J Peripher Nerv Syst
europepmc   +1 more source

FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Selecting Optimized Dosages for Registrational Trials. [PDF]

Clin Cancer Res
Shord SS, Chen C, Jin JY, Van Wart S, Martin SK, Davidson BA, Liu J, LoRusso PM, Oxnard GR.   +8 more
europepmc   +1 more source

PHARMACODYNAMICS OF ALFENTANIL AS A SUPPLEMENT TO NITROUS OXIDE ANAESTHESIA IN THE ELDERLY PATIENT

, 1988
Harry J. M. Lemmens, A. G. L. Burm, James G. Bovill, P. J. Hennis   +3 more
openalex   +1 more source

Citrus Flavonoids for Cystic Fibrosis Treatment

ChemBioChem, EarlyView.
Studies conducted since the late 1990s show substantial activity of selected citrus flavonoids as cystic fibrosis transmembrane conductance regulator (CFTR) membrane protein activators. The thesis of this work is that aptly formulated citrus flavonoids hold sigificant potential for developing a multitarget treatment of cystic fibrosis combining in a ...
Mario Pagliaro, Caterina Di Sano, Claudia D'Anna, Giovanna Li Petri, Giuseppe Angellotti, Rosaria Ciriminna   +5 more
wiley   +1 more source

A Comparison of in-vitro Pharmacokinetics and Pharmacodynamics of Branded and Its Locally Produced Cefuroxime Sodium Against <i>Staphylococcus</i> and <i>Escherichia Escherichia coli</i>. [PDF]

Drug Des Devel Ther
Du M, Sun T, Wang X, Chi X, Xiao Y.
europepmc   +1 more source

Influence of alpha-chloralose on muscle relaxant effect of chlorzoxazone in rats and pharmacodynamic analysis.

, 1989
Ikue Kaneko, Yoshinobu Fukumori, Tomoaki Fukuda, Yoshikazu TAKEUCHI   +3 more
openalex   +2 more sources

Comparison of Fixed‐Dose Clopidogrel/Asetylsalicylic Acid Combination and Standard Loading Strategy During Percutaneous Coronary Intervention in Chronic Coronary Syndrome

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Dual antiplatelet therapy (DAPT), comprising acetylsalicylic acid and a P2Y12 receptor inhibitor such as clopidogrel, is the cornerstone of management in patients undergoing percutaneous coronary intervention (PCI). While conventional loading doses of acetylsalicylic acid and clopidogrel are well established, there is limited ...
Ahmet Anıl Başkurt, Oktay Şenöz, Yusuf Demir, Eren Ozan Bakır, Ferhat Siyamend Yurdam, Ecem Gürses, İlhan Koyuncu, Ahmet Erseçgin, Saadet Aydın, Zeynep Yapan Emren, İlker Gül   +10 more
wiley   +1 more source