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Sensitivity analysis of pharmacodynamic parameters in pharmacodynamic models
European Journal of Drug Metabolism and Pharmacokinetics, 2001The quantitative properties of a pharmacodynamic model can be characterized by the pharmacodynamic parameters. The sensitivity analysis of pharmacodynamic parameters in eight kinds of pharmacodynamic models was conducted. The sensitivity functions with respect to different pharmacodynamic parameters for these pharmacodynamic models were deduced using ...
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Pharmacodynamic bioequivalence testing [PDF]
Journal of Clinical Pharmacy and Therapeutics, 2012 The assessment of bioequivalence of drugs intended for local action/targeted delivery and with poor systemic absorption presents unique challenges. Approaches such as pharmacodynamic (PD) bioequivalence testing have been proposed as alternatives to pharmacokinetic (PK) bioequivalence studies.
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Pharmacokinetics and pharmacodynamics in the newborn
Veterinary Research Communications, 2008Pharmacokinetics and pharmacodynamics in the newborn are multifaceted: maturation processes of the systems committed to absorption, distribution, metabolism, and excretion partially overlap, making the newborn an extremely dynamic system, especially if compared with adults.
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Introduction and Pharmacodynamics
2019Pharmacologically active substances comprise drugs and poisons. Drugs possess therapeutically beneficial, and poisons possess deleterious effects. Drugs should be named by their INNs and not by their brand names. There are substantial cultural differences in the use of a given drug in various countries.
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THE PHARMACODYNAMICS OF HISTAMINE
Annals of the New York Academy of Sciences, 1950openaire +3 more sources