Results 1 to 10 of about 34,651 (222)
Preregistration of high‐quality protocols in pharmacoepidemiology research [PDF]
JCPP AdvancesPharmacoepidemiology studies are an important complement to Randomized Clinical trials, but such studies face several challenges, such as confounding and selective reporting.
Henrik Larsson +2 more
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Clinical Therapeutics, 2019 At the time of their marketing authorization, the effects of drugs and especially their efficacy have been mostly studied in randomized controlled clinical trials (RCT), comparing them to placebo or to existing drugs. However, RCT are by nature limited in their extent, and the often stringent inclusion and exclusion criteria destined to provide for ...
Nicholas, Moore +2 more
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Journal of Clinical Medicine, 2023 The aims of this review are to provide a comprehensive overview of the definition and scope of pharmacoepidemiology, to summarize the study designs and methodologies used in the field, to discuss the future trends in the field and new methodologies to address bias and confounding, and finally to give some recommendations to clinicians interested in ...
Sabaté, Mònica|| +1 more
+8 more sources
JID Innovations, 2023 The U.S. Food and Drug Administration and clinical guidelines use evidence from pharmacoepidemiology studies to inform prescribing decisions and fill evidence gaps left by randomized controlled trials (RCTs).
Sebastian Schneeweiss +1 more
doaj +1 more source
Pharmacoepidemiology, 2023 Though it is well documented that antidepressants are associated with an increased risk of falls in older adults at the drug class level, the comparative risk between individual antidepressants for fall injury in older adults with depression is unknown ...
Ashley Tabah +3 more
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Pharmacoepidemiology, 2023 Background: Medicines information (MI) is a specialist area of pharmacy that provides evidence-based answers to often complex medication queries, utilising resources such as textbooks and databases.
Jeanie Misko, Matthew D. M. Rawlins
doaj +1 more source
Pharmacoepidemiology, 2023 Heart disease and cancer are the main causes of morbidity and mortality worldwide. As the number of cancer survivors increases, cardiotoxicity associated with cancer treatment has become a major concern as it presents a substantial challenge in the ...
Karolini Zuqui Nunes +7 more
doaj +1 more source
Pharmacoepidemiology, 2023 Irrational and inappropriate prescribing of antibiotics is a major problem that can lead to the development of antimicrobial resistance (AMR). In Zambia, there is insufficient information on the prescribing patterns of antibiotics according to the World ...
Steward Mudenda +19 more
doaj +1 more source
How pharmacoepidemiology networks can manage distributed analyses to improve replicability and transparency and minimize bias [PDF]
, 2020 Several pharmacoepidemiology networks have been developed over the past decade that use a distributed approach, implementing the same analysis at multiple data sites, to preserve privacy and minimize data sharing.
Brown, Jeffrey S. +5 more
core +2 more sources