Results 161 to 170 of about 36,199 (325)

A Retrospective Analysis of the Clinical Effectiveness of Tigecycline in the Treatment of Clostridioides difficile-Associated Diarrhea

Pharmacoepidemiology
Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea in the United States. Tigecycline has been proposed as a potential treatment for CDI, though limited clinical data exist to support this practice.
Herman Joseph Johannesmeyer, Luiza Baloyan, Kristica Kolyouthapong   +2 more
doaj   +1 more source

Evolving Recommendations for Patient Populations Among Oncology Medicines: A Quantitative and Qualitative Analysis

Clinical Pharmacology &Therapeutics, Volume 118, Issue 1, Page 95-105, July 2025.
After a medicine has been tested in pivotal trials, regulators, health technology assessment (HTA) organizations, and professional societies make decisions about the patients best served by the medicine. This study assesses how the patient populations for oncology medicines (2010–2023) are defined (1) at trial, (2) regulatory submission, (3) upon ...
Milou A. Hogervorst, Rick A. Vreman, Theresa A. Oduol, Aukje K. Mantel‐Teeuwisse, Wim G. Goettsch, Aaron S. Kesselheim   +5 more
wiley   +1 more source

Adverse Drug Reactions in Multimorbid Older People Exposed to Polypharmacy: Epidemiology and Prevention

Pharmacoepidemiology
Adverse drug reactions (ADRs) are frequent and represent a significant healthcare burden. ADRs are a potentially avoidable contributor to excess unscheduled hospital admissions, higher morbidity, mortality, and healthcare costs.
Siobhán McGettigan, Denis Curtin, Denis O’Mahony   +2 more
doaj   +1 more source

Modeling Versus Balancing Approaches to Addressing Instrumental Variables in Weighting: A Comparison of the Outcome‐Adaptive Lasso, Stable Balancing Weighting, and Stable Confounder Selection

Pharmacoepidemiology and Drug Safety, Volume 34, Issue 7, July 2025.
ABSTRACT Background Variable selection is essential for propensity score (PS)‐weighted estimators. Recent work shows that including instrumental variables (IVs), associated with only treatment but not with the outcome, can impact both the bias and precision of the PS‐weighted estimators.
Byeong Yeob Choi, M. Alan Brookhart
wiley   +1 more source

Moral distress among maternity and neonatal healthcare workers during the COVID‐19 pandemic in Sweden: Results from the COPE staff longitudinal cohort study

Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 7, Page 1399-1409, July 2025.
Maternity and neonatal healthcare workers in Sweden experienced moral distress during the COVID‐19 pandemic, linked to uncertain staffing, continuity‐of‐care challenges, and limited opportunities for patient/family counseling. Addressing these issues is crucial to safeguard their well‐being during future healthcare crises.
Patricia Ernst, Karolina Linden, Marta Roczniewska, Emina Hadzibajramovic, Anna Wessberg, Ola Andersson, Ylva Carlsson, Sofie Graner, Maria Jonsson, Malin Veje, Verena Sengpiel, Magnus Akerstrom   +11 more
wiley   +1 more source

Pharmacoepidemiology. [PDF]

, 2001
Richard Martin
openalex   +1 more source

Unmeasured confounding in pharmacoepidemiology [PDF]

Annals of Epidemiology, 2016
Groenwold, Rolf H. H.; de Groot, Mark C. H.; Ramamoorthy, Dhivya; Souverein, Patrick C.; Klungel, Olaf H.   +5 more
openaire   +5 more sources

Glucocorticoid‐induced hyperglycaemia in hospitalised adults: A matched cohort study (2013–2023)

Diabetes, Obesity and Metabolism, Volume 27, Issue 7, Page 3635-3644, July 2025.
Abstract Aims To compare the risk of new‐onset hyperglycaemia between inpatients treated versus non‐treated with systemic glucocorticoids and identify factors associated with glucocorticoid‐induced hyperglycaemia (GIH). Materials and methods We conducted a cohort study using electronic healthcare records of adults admitted to the Oxford University ...
Rajna Golubic, Hudson Mumbole, Ruth L. Coleman, Rustam Rea, Rohini Mathur, Rishi Caleyachetty, Amanda I. Adler   +6 more
wiley   +1 more source

Utilization of Real-World Data to Facilitate Clinical Trials for Patients with Lymphoma

Pharmacoepidemiology
The future directions in leveraging real-world evidence (RWE) and real-world data (RWD) in the field of lymphoma, as compared to traditional experimental clinical trials, are poised to significantly impact research methodologies, treatment strategies ...
Dai Chihara, Brian P. Hobbs, Matthew J. Maurer, Christopher R. Flowers   +3 more
doaj   +1 more source

Association between the body mass index and risk of cardiovascular events in sodium‐glucose cotransporter 2 inhibitor users compared with dipeptidyl‐peptidase 4 inhibitor users: A nationwide cohort study in Korea

Diabetes, Obesity and Metabolism, Volume 27, Issue 7, Page 3869-3881, July 2025.
Abstract Aims There is limited evidence regarding whether obesity modifies the association between the use of sodium‐glucose cotransporter 2 inhibitors (SGLT2is) and the risk of cardiovascular events. We assessed whether baseline body mass index (BMI) modifies the association between SGLT2i use and the risk of major adverse cardiovascular events (MACE)
Hwa Yeon Ko, Kyungyeon Jung, Yongtai Cho, Sungho Bea, Jae Hyun Bae, Young Min Cho, Sang Youl Rhee, Ju‐Young Shin   +7 more
wiley   +1 more source