Results 141 to 150 of about 35,320 (249)

Identifying the Initiation of a New Line of Therapy for Metastatic Lung, Breast, and Colorectal Cancer in Real‐World Data: A Scoping Review

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose This study aimed to identify and synthesize published algorithms for identifying the initiation of a new line of therapy (LOT) for metastatic lung, breast, and colorectal cancer in real‐world data (RWD). Methods We conducted a scoping review of published, English‐language studies describing algorithms for identifying any LOTs with ...
Oluwadamilola Onasanya, Seyed Hamidreza Mahmoudpour, Benjamin Bates, Irene M. Shui, Geoffrey Liu, Eng Hooi Tan, Yi‐Hsin Yang, Maribel Salas, Joseph Fadare, Dimitri Bennett, Paula Lana de M. Drummond, Judy Ju‐Young Shin, Sonia Guleria, Jocelyn R. Wang, Manila Hada, Helene Denis, Soko Setoguchi, Ilse Truter, Luciane C. Lopes, Ruth Wangia Dixon   +19 more
wiley   +1 more source

A Systematic Review to Summarize and Critically Appraise Existing Phenotype Libraries Using Electronic Health Records

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose Pharmacoepidemiology and population health studies using electronic health care records (EHRs) must define study variables through available electronic data. These variables are operationalized through phenotypes, which are a defined set of criteria used to identify specific traits or medical conditions.
Sima Mohammadi, Cori Campbell, Miriam C. J. M. Sturkenboom, Tiago A. Vaz   +3 more
wiley   +1 more source

The Contribution to the Assignment of Defined Daily Dose (DDD) to Antineoplastic Drugs of the Italian Working Group on DDD

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose To report the experience of the Italian Working Group on DDD (Ita‐DDD‐wg) in assigning DDDs to a list of antineoplastic agents. Methods Active substances from the ATC L01 group with no assigned DDD and reimbursed at least once during 2021 by the Italian Healthcare Service were identified.
Angela Boccia, Giulia Hyeraci, Anna Girardi, Rosa Gini, Gianluca Trifirò, Ylenia Ingrasciotta, Andrea Spini, Valentina Ientile, Elisabetta Poluzzi, Giampiero Mazzaglia, Ippazio Cosimo Antonazzo, Casula Manuela, Elena Tragni, Olivia Leoni, Arianna Mazzone, Michele Ercolanoni, Martina Zanforlini, Ursula Kirchmayer, Belleudi Valeria, Marco Finocchietti, Francesco Barone‐Adesi, Giuseppe Roberto   +21 more
wiley   +1 more source

Delayed Exposures and Pre‐Exposure Periods in Self‐Controlled Case Series Studies

Statistics in Medicine, Volume 45, Issue 10-12, May 2026.
ABSTRACT A key assumption of the self‐controlled case series (SCCS) method is that exposures should not depend on the event of interest. However, treatments such as vaccines may be deferred after an adverse health event. One suggestion to handle such delayed exposures is to include a pre‐exposure window in the SCCS model.
Heather Whitaker, Yonas Ghebremichael Weldeselassie, Paddy Farrington   +2 more
wiley   +1 more source

Impact of Evolving Evidence on Pharmacological Therapy for Alcohol‐Associated Hepatitis in Alberta: A Population‐Based Study of Practice Trends and MELD‐Stratified Effectiveness of Corticosteroids

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 9, Page 1246-1255, May 2026.
In this population‐based study in Alberta, Canada, evidence from RCTs led to a rapid reversal in pentoxifylline use, prior to formal guideline updates. Real‐world data support a modest short‐term benefit of CS and illustrate the potential of target trial emulation to assess treatment effectiveness in specific groups of patients. ABSTRACT Background and
Abdel‐Aziz Shaheen, Meng Wang, Bryce Tkachuk, Juan G. Abraldes   +3 more
wiley   +1 more source

Baseline and 4‐year associations between prediabetes and kidney impairment: Insights from the ILERVAS cohort

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3777-3787, May 2026.
Abstract Aims Prediabetes is a prevalent condition associated with increased cardiovascular and renal risk. However, the long‐term impact of haemoglobin A1c (HbA1c) within the range defined as prediabetes on kidney function remains unclear. This study aimed to evaluate the association between prediabetes and renal function (estimated glomerular ...
Aitziber Izarra, Marcelino Bermúdez‐López, José M. Valdivielso, Reinald Pamplona, Gerard Torres, Dídac Mauricio, Eva Castro‐Boqué, Elvira Fernández, Rafael Simó, Cristina Hernández, Albert Lecube, on behalf of the ILERVAS project collaborators, Eva Miquel, Marta Ortega, Ferran Barbé, Jordi de Batlle, Jessica González, Manuel Portero‐Otín, Mariona Jové, Josep Franch‐Nadal, Esmeralda Castelblanco, Pere Godoy, Montse Martinez‐ Alonso, Cristina Farràs   +23 more
wiley   +1 more source

Curriculum in Pharmacoepidemiology Training Programs: A Cross-Sectional Study to Assess Educational Needs and Alignment With Core Competencies. [PDF]

Pharmacoepidemiol Drug Saf
Goodin A, Layton D, Chung R, Osborne V, Ejekam C, Li X, Wen X, Filion KB, Lopes LC, Moga DC.   +9 more
europepmc   +1 more source

Depression following the initiation of glucagon‐like‐peptide‐1 receptor agonist therapy: A multinational self‐controlled case series study

Journal of Internal Medicine, Volume 299, Issue 6, Page 776-780, June 2026.
Vincent Ka Chun Yan, Zi‐Yang Peng, Vincent Kai Chung Wong, Ian Chi Kei Wong, Esther Wai Yin Chan, Huang‐Tz Ou, Eric Yuk Fai Wan   +6 more
wiley   +1 more source

Impact of early and tight HbA1c control on the risk of long‐term complications and cardiovascular death in patients with type 2 diabetes from the Swedish National Diabetes Register

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3997-4009, May 2026.
Abstract Aims To assess the relationship between haemoglobin A1c (HbA1c) levels and incidence of long‐term complications in patients with type 2 diabetes (T2D). Materials and Methods This long‐term, retrospective study acquired patient data from the Swedish National Diabetes Registry and linked national registers between 1 January 1998 and 31 December ...
Julie Mount, Kristina Boye, Jeremie Lebrec, Emily Wilkes, Kari Ranta, Anders Toll, Erik Joas, Irina Sveide, Björn Eliasson, Josefine Redig   +9 more
wiley   +1 more source

Strategies to Enhance Satisfaction and Success in an Academic Career in Pharmacoepidemiology. [PDF]

Pharmacoepidemiol Drug Saf
Lo Re V, Bushnell G, Lopes LC, Pottegård A.   +3 more
europepmc   +1 more source