Results 131 to 140 of about 35,320 (249)
Aims: The aim of this study was to explore the suspected adverse drug reaction (ADR) data of five licensed statins in the UK: atorvastatin, fluvastatin, pravastatin, rosuvastatin, and simvastatin.
Hasan Yousaf, Alan M. Jones
doaj +1 more source
Involuntary Clozapine Treatment: A Systematic Review
ABSTRACT Introduction We aimed to synthesize the information relevant for clinical practice on involuntary clozapine treatment. Methods Articles were identified with MEDLINE, Web of Sciences and PsycINFO search from inception through September 2025 (PROSPERO database registration CRD420251234475).
Hélène Verdoux +2 more
wiley +1 more source
Buprenorphine is a safe and effective medication to treat opioid use disorder (OUD) in pregnant patients and is intended to be continued throughout pregnancy, delivery, and at least the one-year postpartum period.
Taylor N. Hallet +6 more
doaj +1 more source
In the real‐world VANESSA study in triple‐negative breast cancer, PD‐L1‐positive prevalence was 38% in early‐stage and 20% in metastatic tumours, lower than in prospective trials. The lower prevalence in smaller versus larger tissue samples and by local versus central assessment underlines the importance of robust PD‐L1 testing to determine eligibility
Corrado D'Arrigo +16 more
wiley +1 more source
Abstract Background Effectively identifying individuals exposed to drug underuse, overuse and potentially inappropriate medication (PIM) in older adults is essential for minimizing preventable drug‐related harms. Methods We analysed data from 54,296 individuals aged 60–74 years from the German National Cohort (NAKO).
Miriam Degen +18 more
wiley +1 more source
ASCPT has a mission to advance clinical pharmacology and translational sciences to reduce health disparities. The development, regulatory, and outcomes (DRO) network within ASCPT strives to advance pharmacoequity globally. Pharmacoequity, coined by Utibe Essien (2021), is the principle that all individuals, regardless of race, ethnicity, geography, or ...
Priya Jayachandran +13 more
wiley +1 more source
Factors associated with response to rituximab in patients with immune thrombocytopenia
Abstract Rituximab is a well‐established treatment for adult immune thrombocytopenia (ITP), with ~60% initial response (IR) and 20%–30% long‐term remissions. We conducted a register‐based cohort study of 759 ITP patients in Sweden, Denmark, and Norway treated with rituximab (2009–2018) to identify factors associated with response.
Galina Tsykunova +7 more
wiley +1 more source
The EUROmediCAT Network and Databases: A Resource for Pharmacovigilance in Pregnancy
ABSTRACT Background The evidence gap relating to the risk of congenital anomalies (CA) associated with first trimester medication exposure in pregnancy is well recognized. Aims We describe the EUROmediCAT network and databases, and the methodological approach to pregnancy pharmacovigilance.
Helen Dolk +27 more
wiley +1 more source

