Results 111 to 120 of about 27,020 (235)

Agreement Between Medico-Administrative Database Algorithms and Survey-Based Diagnoses for Depression and Anxiety in Older Adults

Pharmacoepidemiology
Objectives: This study aimed to assess the concordance between depression and anxiety case definitions derived from algorithms based on medico-administrative data and structured interviews aligned with the fourth edition of the Diagnostic and Statistical
Giraud Ekanmian, Carlotta Lunghi, Helen-Maria Vasiliadis, Line Guénette   +3 more
doaj   +1 more source

Predicting the Long‐Term Risk of Type 2 Diabetes and Cardiovascular Disease With Orforglipron in People With Overweight or Obesity: A Post Hoc Analysis of the ATTAIN‐1 Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11452-11462, December 2026.
ABSTRACT Objective To assess change in long‐term predicted 10‐year cardiometabolic risk (Type 2 diabetes [T2D] and cardiovascular disease [CVD]) in adults with overweight or obesity without T2D. Methods This post hoc analysis used data from ATTAIN‐1, a Phase 3 trial in adults (≥ 18 years) with obesity (BMI ≥ 30 kg/m2) or overweight (BMI ≥ 27 kg/m2 with
Shraddha Shinde, Florian Kahles, Simona Vasileva‐Metodiev, Ryan Griffin, Hong Liu‐Seifert, Jeremie Lebrec, Neena A. Xavier, Runjia Li, Suzanne R. Klise, Ambrish Singh, Jens Aberle   +10 more
wiley   +1 more source

The Asian Pharmacoepidemiology Network (AsPEN) : promoting multi-national collaboration for pharmacoepidemiologic research in Asia

The Asian Pharmacoepidemiology Network (AsPEN) is a multi-national research network, which was formed to provide a mechanism to support the conduct of pharmacoepidemiological research and to facilitate the prompt identification and validation of emerging
Setoguchi, Soko, Sundström, Anders, Shin, Ju-Young, Park, Byung-Joo, Roughead, Elizabeth E., Kimura, Tomomi, Ooba, Nobuhiro, Kubota, Kiyoshi, Bergman, Ulf, Andersen, Morten, Kimura, Michio, Jalbert, Jessica, Huang, Cecilia, Lai, Edward Chia-Cheng, Choi, Nam-Kyong, Gerhard, Tobias, Sato, Tsugumichi, Yang, Yea-Huei Kao, Pratt, Nicole   +18 more
core  

Sex and Socioeconomic Differences in the Initiation of SGLT2 Inhibitors and GLP‐1 Receptor Agonists in Patients With Type 2 Diabetes and Cardiovascular Disease: A Nationwide Cohort Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11664-11675, December 2026.
ABSTRACT Aims Cardioprotective glucose‐lowering drugs (GLDs) remain underutilised in individuals with Type 2 diabetes (T2D) and cardiovascular disease (CVD). We aimed to estimate the association between sex and socioeconomic status and initiation of cardioprotective GLDs and to identify factors associated with non‐initiation of cardioprotective GLDs ...
Elena Calderon, Lasse Bjerg, Anders A. Isaksen, Annelli Sandbæk, Kristian L. Funck, Erik L. Grove   +5 more
wiley   +1 more source

Antibiotic Prescribing for Group B Streptococcus Coverage in Preterm Prelabour Rupture of Membranes: A Retrospective Cohort Study

Pharmacoepidemiology
Background: Preterm prelabour rupture of membranes (PPROM) is the spontaneous rupture of fetal membranes prior to 37 weeks of pregnancy. Latency antibiotics, including macrolides with or without group B streptococcus (GBS)-covering antibiotics, are ...
Elaf Abuelgasim, Mark McIntyre, Najla Tabbara   +2 more
doaj   +1 more source

Aumolertinib Versus Osimertinib as First‐Line Treatment for EGFR‐Mutant Non‐Small Cell Lung Cancer: A Retrospective Real‐World Multicenter Study

International Journal of Cancer, Volume 159, Issue 10, Page 2575-2584, 15 November 2026.
As third‐generation EGFR‐tyrosine kinase inhibitors, both aumolertinib and osimertinib demonstrate clinical efficacy for non‐small cell lung adenocarcinoma, especially in patients with brain metastases. Currently, head‐to‐head studies comparing these two agents in real‐world settings are scarce.
Jinxia Wang, Ping Qi, Jinhua Li, Na Wang, Caihong Fu, Lixin Liu, Shuping Li, Xiao Li, Xiaoming Hou, Hui Qiao   +9 more
wiley   +1 more source

Exploratory Signal Detection of Maternal and Perinatal Adverse ART Drug Events in EudraVigilance: Insights from Network and Cluster Analyses

Pharmacoepidemiology
Background: Medication safety in pregnancy, puerperium, and perinatal periods is underexplored because these populations are excluded from clinical trials.
Bárbara Costa, Nuno Vale
doaj   +1 more source

Standardization of measurement and reporting of medication adherence using the TEN‐SPIDERS tool for claims data

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3778-3789, November 2026.
This study provides the first open‐source tool to implement the complete TEN‐SPIDERS framework in linked datasets for the determination of the PDC for medication adherence. The TEN‐SPIDERS tool enables transparent, reproducible medication adherence research through automated reporting of all calculation parameters and flexible customization options ...
Adam C. Livori, Tzu‐Yung Kuo, Jenni Ilomäki, Monique F. Kilkenny, Stella Talic, Zanfina Ademi, J. Simon Bell, Jedidiah I. Morton, Lachlan L. Dalli   +8 more
wiley   +1 more source

Hepatobiliary Adverse Events Associated with Pembrolizumab: A Pharmacovigilance Study from the FDA Adverse Event Reporting System (FAERS) Database

Pharmacoepidemiology
Background: Immuno-oncology has transformed cancer treatment, with immune checkpoint inhibitors (ICIs) like pembrolizumab playing a key role. While highly effective, these therapies can also cause immune-related adverse events.
Connor Frey
doaj   +1 more source

Impact of parameter settings on the estimation of drug exposure with the individualized dispensing patterns method

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3982-3991, November 2026.
Aim To assess the impact of parameter settings when using the individualized dispensing patterns (IDP) method to estimate exposure duration from dispensing data. Methods We conducted a cohort study using a 2% representative sample of the French healthcare insurance database from 2013 to 2022.
Laëtitia Gosselin, Clara Lévy, Noémie Sève, Thierry Blanchon, Marianne Sarazin, Louise Rossignol, Maryse Lapeyre‐Mestre, Nathanaël Lapidus, Olivier Steichen   +8 more
wiley   +1 more source