Results 101 to 110 of about 27,665 (215)

The real‐world relationship between naltrexone/bupropion treatment and weight loss in Canada: A retrospective chart review

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton, Elham Kamran, Lehana Thabane, Peter Yin, Rebecca Christensen   +4 more
wiley   +1 more source

Post-Marketing Pharmacovigilance Study of Darunavir in the United Kingdom: An Analysis of Adverse Drug Reactions Reported to the MHRA

Pharmacoepidemiology
Background/Objectives: Human immunodeficiency virus (HIV) continues to be a global public health concern. Several antiretroviral drugs have been approved for the treatment, post-exposure, and pre-exposure prophylaxis of HIV. Darunavir (DRV) is a protease
Pono Pono, Vicky Cheng, Victoria Skerrett, Alan M. Jones   +3 more
doaj   +1 more source

Core concepts in pharmacoepidemiology: multi-database distributed data networks [PDF]

Multi-database distributed data networks for post-marketing surveillance of drug safety and effectiveness use two main approaches: common data models (CDMs) and common protocols. Networks such as the U.S.
Prieto-Alhambra, Daniel, B. Filion, Kristian, Haber, Rachelle, Maro, Judith C., Prieto-Alhambra, D., Li, X., Platt, Robert W., Filion, Kristian B., Prieto Alhambra, Daniel, Maro, J.C., Haber, R., W. Platt, Robert, Barclay, N., Li, Xue, Platt, R.W., Webster-Clark, Michael, Pratt, Nicole, Webster-Clark, M., Filion, K.B., Barclay, Nicola, Pratt, N., C. Maro, Judith   +21 more
core   +1 more source

Tirzepatide Persistence and Associated Changes in Clinical Outcomes in US Adults With Obesity or Overweight: A 6‐Month Claims Database Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Tirzepatide is a once‐weekly glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) approved in the US for the treatment of Type 2 diabetes (T2D), weight loss and obstructive sleep apnoea. This study aimed to assess the utilisation and effectiveness of tirzepatide among individuals in a large ...
Theresa Hunter Gibble, Malvika Venkataraman, Donna Mojdami, Carlos Vallarino, Grace Stockbower, Michael Grabner, Mythili Ananth, Karishma Desai   +7 more
wiley   +1 more source

Antipsychotic Drugs and Diabetic Ketoacidosis: A Disproportionality Analysis of the FDA Adverse Event Reporting System

Pharmacoepidemiology
Objectives: To evaluate reports of diabetic ketoacidosis (DKA) associated with antipsychotic drug (APD) use submitted to the U.S. Food and Drug Administration’s Adverse Event Reporting System (FAERS).
Nisrine Haddad, Abdallah Alami, Christopher A. Gravel, Derek Tsui, Yue Chen, Franco Momoli, Donald Mattison, Nawal Farhat, Daniel Krewski   +8 more
doaj   +1 more source

Melatonin in sleepless children : everything has a rhythm? [PDF]

, 2011
Every living organism has an biological clock regulating endogenous melatonin production, synchronized by exogenous impulses like daylight, temperature and feeding. Inappropriately applied bright light disturbs this melatonin rhythm.
Pharmacoepidemiology, van Geijlswijk, I.M., Sub Pharmacoepidemiology   +2 more
core   +1 more source

Increasing Trends in Hospitalisation With Diabetic Ketoacidosis at Type 1 Diabetes Diagnosis Among Children and Youth in the United States and England, 2002–2020

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background There is a paucity of population‐level data evaluating trends in the proportion of children and youth hospitalised with diabetic ketoacidosis (DKA) at the time of Type 1 diabetes (T1D) diagnosis. Methods National Medicaid (US publicly insured claims), MarketScan (US commercially insured claims) and Clinical Practice Research ...
Chintan V. Dave, Kristen Lloyd, Abner Nyandege, Jason Roy, Raquel López‐Díez, Sally Radovick, Brian L. Strom   +6 more
wiley   +1 more source

The Asian Pharmacoepidemiology Network (AsPEN) : promoting multi-national collaboration for pharmacoepidemiologic research in Asia

The Asian Pharmacoepidemiology Network (AsPEN) is a multi-national research network, which was formed to provide a mechanism to support the conduct of pharmacoepidemiological research and to facilitate the prompt identification and validation of emerging
Setoguchi, Soko, Sundström, Anders, Shin, Ju-Young, Park, Byung-Joo, Roughead, Elizabeth E., Kimura, Tomomi, Ooba, Nobuhiro, Kubota, Kiyoshi, Bergman, Ulf, Andersen, Morten, Kimura, Michio, Jalbert, Jessica, Huang, Cecilia, Lai, Edward Chia-Cheng, Choi, Nam-Kyong, Gerhard, Tobias, Sato, Tsugumichi, Yang, Yea-Huei Kao, Pratt, Nicole   +18 more
core  

Drug Repurposing for Parkinson's Disease Prevention: Replication Study of Three Drugs in French Healthcare Databases

Movement Disorders, EarlyView.
Yanis Saidi, Anne Paakinaho, Eeva Pylkkö, Sirpa Hartikainen, Anna‐Maija Tolppanen, Alexis Elbaz, Ismaïl Ahmed, Anne C.M. Thiébaut, Émeline Courtois   +8 more
wiley   +1 more source

Cohort and Case–Control Studies: Strengths, Limitations and Methodological Considerations

Journal of Periodontal Research, EarlyView.
Population‐based epidemiology and clinical research are complementary by design—and nowhere is that more evident than in cohort studies. By following individuals over time, cohorts quantify disease incidence, elucidate environmental and social determinants and evaluate biomarkers and prognostic outcomes within a single longitudinal framework.
Nasir Z. Bashir, João Botelho, John Rong Hao Tay, Dian Yi Chow, Gustavo G. Nascimento   +4 more
wiley   +1 more source