Results 81 to 90 of about 19,579 (254)

Anticholinergic Medication Use in Veterans Affairs Long‐Term Care Residents: Clinical Patterns and Opportunities for Deprescribing

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Anticholinergic exposure is common in nursing homes; however, the true burden may be underestimated, particularly due to over‐the‐counter agents such as first‐generation antihistamines that are not consistently captured in prior claims‐based studies.
Cellas A. Hayes, Yongmei Li, Bocheng Jing, Laura A. Graham, Chintan Dave, Michelle C. Odden   +5 more
wiley   +1 more source

Antipsychotic Drugs and Diabetic Ketoacidosis: A Disproportionality Analysis of the FDA Adverse Event Reporting System

Pharmacoepidemiology
Objectives: To evaluate reports of diabetic ketoacidosis (DKA) associated with antipsychotic drug (APD) use submitted to the U.S. Food and Drug Administration’s Adverse Event Reporting System (FAERS).
Nisrine Haddad, Abdallah Alami, Christopher A. Gravel, Derek Tsui, Yue Chen, Franco Momoli, Donald Mattison, Nawal Farhat, Daniel Krewski   +8 more
doaj   +1 more source

Cohort and Case–Control Studies: Strengths, Limitations and Methodological Considerations

Journal of Periodontal Research, EarlyView.
Population‐based epidemiology and clinical research are complementary by design—and nowhere is that more evident than in cohort studies. By following individuals over time, cohorts quantify disease incidence, elucidate environmental and social determinants and evaluate biomarkers and prognostic outcomes within a single longitudinal framework.
Nasir Z. Bashir, João Botelho, John Rong Hao Tay, Dian Yi Chow, Gustavo G. Nascimento   +4 more
wiley   +1 more source

Medication Exposure Definitions in Perinatal Pharmacoepidemiology: Implications for Pregnancy Studies

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Exposure definitions in real‐world pregnancy studies vary across studies, data sources, treatments and outcomes, yet their impact on prevalence estimates remains unexamined. Objectives To identify the most used exposure definitions during the 1st trimester and evaluate their impact on prevalence estimates: Methods We reviewed 400 ...
Gabra Nohmie, Anick Bérard, Anton Pottegård, Mette Bliddal   +3 more
wiley   +1 more source

Use of Attention Deficit Hyperactivity Disorder Medication Among Danish Children and Adolescents From 2010 to 2023

Acta Psychiatrica Scandinavica, Volume 154, Issue 3, Page 203-211, September 2026.
ABSTRACT Introduction Pharmacological treatment is an important component in the multimodal management of attention deficit hyperactivity disorder (ADHD), but contemporary trends in ADHD medication use among boys and girls in Denmark have not been fully characterized.
Maria Højgaard Stoltz‐Andersen, Martin Thomsen Ernst, Søren Dalsgaard, Lotte Rasmussen, Rikke Wesselhoeft   +4 more
wiley   +1 more source

Deprescription of Psychotropics in Children and Adolescents: Systematic Review of Guidelines and Development of a Deprescribing Algorithm

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background Psychotropics are increasingly prescribed in paediatrics despite limited evidence regarding their benefits and effectiveness. Although deprescribing approaches are established in adults, structured paediatric strategies remain poorly defined.
Paul‐Benoît Fargier, Mark Horowitz, Rodolphe Charles, Valérie Rousselon, Erik Fakra, Marie‐Noëlle Beyens, Marie‐Laure Laroche   +6 more
wiley   +1 more source

Adjunctive Vortioxetine in Major Depressive Disorder with Inadequate Response to Antidepressants: A Prospective Real-World Pilot Study from Malaysia

Pharmacoepidemiology
Background: A significant percentage of patients with major depressive disorder (MDD) fail to achieve remission with antidepressant monotherapy and frequently experience residual mood and cognitive symptoms that impair their functional recovery. Thus, an
Tharishini Ramachandran, Chong Guan Ng, Julian Joon Ip Wong, Aida Syarinaz Ahmad Adlan   +3 more
doaj   +1 more source

Real‐World Evidence of the Effectiveness and Safety of Biosynthetic Semaglutide in Type 2 Diabetes: A Multicentre Study From Pakistan

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8438-8451, September 2026.
ABSTRACT Aims To evaluate the real‐world effectiveness, safety and patient‐reported outcomes of biosynthetic semaglutide in adults with type 2 diabetes mellitus (T2DM) receiving routine outpatient care in a cost‐constrained setting. Methods This 30‐week, prospective, multicentre, non‐interventional study enrolled adults with T2DM initiating ...
Arshad Hussain, Muhammad Umar Wahab, Saleem Qureshi, Umar Yousaf Raja, Atif Munir, Shahnawaz Gardezi, Musarrat Iqbal, Bilal Afzal, Muhammad Daoud Butt, Siew Chin Ong   +9 more
wiley   +1 more source

Determinants and Temporal Trends of Inappropriate Azithromycin Use in Hospitalized Adults with COVID-19: A Retrospective Pharmacoepidemiologic Cohort Study

Pharmacoepidemiology
Background: The COVID-19 pandemic was associated with extensive empirical antibiotic exposure despite the predominantly viral etiology of the disease. Evaluating patterns of azithromycin use, prescribing determinants, and appropriateness provides insight
Fitim Alidema, Arieta Hasani Alidema, Miranda Sejdiu Abazi, Saranda Sejdiu Sadiku, Arben Abazi   +4 more
doaj   +1 more source

Dermatological Disease at a Tertiary Military Hospital in Burundi: A Retrospective Review

International Journal of Dermatology, EarlyView.
Doriane Sabushimike, Alison K. Wright, Marc Nimburanira, Patrick Budengeri, Christopher E. M. Griffiths, Darren M. Ashcroft   +5 more
wiley   +1 more source