Results 71 to 80 of about 19,579 (254)

Impact of Long-Term Statin Therapy on Influenza Incidence and Overall Mortality: A Real-World Data Analysis

Pharmacoepidemiology
Background/Objectives: The study’s goal is to assess the association between long-term statin therapy and influenza incidence, influenza severity, and all-cause mortality.
Diana Toledo, Àurea Cartanyà-Hueso, Constança Pagès-Fernández, Rosa Morros, Maria Giner-Soriano, Àngela Domínguez, Carles Vilaplana-Carnerero, Alba Tor-Roca, María Grau   +8 more
doaj   +1 more source

Time to Insulin Initiation Among Patients With Type 2 Diabetes Treated With Second‐Line Antidiabetic Drugs

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective To examine the effect of second‐line treatments (insulin secretagogues, thiazolidinediones, glucagon‐like peptide‐1 (GLP‐1) receptor agonists, dipeptidyl peptidase‐4 (DPP‐4) inhibitors or sodium‐glucose co‐transporter 2 (SGLT‐2) inhibitors) on time to insulin initiation among patients with type 2 diabetes.
Ya‐Hui Yu, Qi Zhang, Estefania Zapata‐Bravo, Robert W. Platt, Pauline Reynier, Oriana H. Y. Yu, Kristian B. Filion   +6 more
wiley   +1 more source

Antibiotic Prescribing for Group B Streptococcus Coverage in Preterm Prelabour Rupture of Membranes: A Retrospective Cohort Study

Pharmacoepidemiology
Background: Preterm prelabour rupture of membranes (PPROM) is the spontaneous rupture of fetal membranes prior to 37 weeks of pregnancy. Latency antibiotics, including macrolides with or without group B streptococcus (GBS)-covering antibiotics, are ...
Elaf Abuelgasim, Mark McIntyre, Najla Tabbara   +2 more
doaj   +1 more source

GLP‐1 RA Plus SGLT2i Versus Monotherapy in MASLD and Type 2 Diabetes: Three Pairwise Target Trial Emulations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated cardiovascular and metabolic benefits individually; however, the comparative effectiveness of combination therapy versus monotherapy in patients with metabolic dysfunction‐associated steatotic liver ...
Mohanad A. Alkuwaiti, Faisal A. Al‐Harbi, Ahmed K. Alsaif, Ziyad M. AlSughayyir, Rayan Saleh Alsaud, Mohammed N. Aljabr, Ahmad K. Alanazi, Ahmad A. Alosaily, Abdulrhman K. Alabdulqader, Hamza Almusabeh, Rayyan F. Altemani, Ahmed Y. Azzam   +11 more
wiley   +1 more source

A Retrospective Analysis of the Clinical Effectiveness of Tigecycline in the Treatment of Clostridioides difficile-Associated Diarrhea

Pharmacoepidemiology
Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea in the United States. Tigecycline has been proposed as a potential treatment for CDI, though limited clinical data exist to support this practice.
Herman Joseph Johannesmeyer, Luiza Baloyan, Kristica Kolyouthapong   +2 more
doaj   +1 more source

Adverse Drug Reactions in Multimorbid Older People Exposed to Polypharmacy: Epidemiology and Prevention

Pharmacoepidemiology
Adverse drug reactions (ADRs) are frequent and represent a significant healthcare burden. ADRs are a potentially avoidable contributor to excess unscheduled hospital admissions, higher morbidity, mortality, and healthcare costs.
Siobhán McGettigan, Denis Curtin, Denis O’Mahony   +2 more
doaj   +1 more source

Using Pooled Electronic Health Records to Conduct Pharmacoepidemiology Safety Studies: Challenges and Lessons Learned

, 2023
Beukelman T, Chen L, Annapureddy N, Oates J, Clowse MEB, Long M, Kappelman MD, Rhee RL, Merkel PA, Nowell Wb, Xie F, Clinton C, Curtis JR   +12 more
openalex   +1 more source

Assessing Associations of Three Types of Higher‐Risk Medication Use and Mortality in Older Adults

Journal of the American Geriatrics Society, EarlyView.
Having a medication regimen with polypharmacy was associated with higher risk of mortality among older adults even after accounting for clinical factors and other types of higher‐risk medication use. ABSTRACT Background Higher‐risk medication use—including regimens with polypharmacy, drug–drug interactions (DDIs), and potentially inappropriate ...
Alexander Chaitoff, Katharina Tabea Jungo, Lillian Min, Donovan T. Maust   +3 more
wiley   +1 more source

Pharmacoepidemiology [PDF]

BMJ, 1984
openaire   +3 more sources

Post-Marketing Pharmacovigilance Study of Darunavir in the United Kingdom: An Analysis of Adverse Drug Reactions Reported to the MHRA

Pharmacoepidemiology
Background/Objectives: Human immunodeficiency virus (HIV) continues to be a global public health concern. Several antiretroviral drugs have been approved for the treatment, post-exposure, and pre-exposure prophylaxis of HIV. Darunavir (DRV) is a protease
Pono Pono, Vicky Cheng, Victoria Skerrett, Alan M. Jones   +3 more
doaj   +1 more source