Results 91 to 100 of about 27,020 (235)

Sharing is caring? International Society for Pharmacoepidemiology review and recommendations for sharing programming code [PDF]

Purpose: There is increasing recognition of the importance of transparency and reproducibility in scientific research. This study aimed to quantify the extent to which programming code is publicly shared in pharmacoepidemiology, and to develop a set of ...
Prieto-Alhambra, Daniel, Gini, Rosa, Donegan, Katherine, Morton, Caroline, Douglas, Ian, Arlett, Peter, Schneeweiss, Sebastian, Logie, John, Tazare, John, Popovic, Jennifer, Schultze, Anna, Wang, Shirley V, Morales Leaver, Daniel R   +12 more
core   +1 more source

Palbociclib in the Treatment of HR+/ HER2‐ Advanced or Metastatic Breast Cancer in Australia: A Real‐World Retrospective Analysis

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This study investigated the real‐world use of CDK4/6 inhibitors in Australian patients with HR+/HER2‐ advanced or metastatic breast cancer, providing data on patient demographics, treatment patterns, and outcomes with palbociclib. ABSTRACT Background There is limited real‐world data on the use of CDK4/6 inhibitors in Australian patients with HR+/HER2 ...
Louise Nott, Eugene Moylan, Maree Colosimo, Giles Stratton, Thomas Chiu, Mahsa H. Kouhkamari, Maureen Hitschfeld, Jessica Michie, Richard De Boer   +8 more
wiley   +1 more source

MCL‐1 inhibition triggers a largely reversible cardiac stress signature in a humanised mouse model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Myeloid cell leukaemia‐1 (MCL‐1) is an essential anti‐apoptotic protein and a promising therapeutic target in oncology. Early clinical studies of MCL‐1 inhibitors reported unexpected elevations in cardiac troponin, raising concerns about potential cardiotoxicity.
Markus B. Heckmann, Zsanett Papdi, Nils J. Strauch, Daniel Finke, Marc‐Steffen Raab, Antje Blank, Norbert Frey, Lorenz H. Lehmann   +7 more
wiley   +1 more source

The real‐world relationship between naltrexone/bupropion treatment and weight loss in Canada: A retrospective chart review

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton, Elham Kamran, Lehana Thabane, Peter Yin, Rebecca Christensen   +4 more
wiley   +1 more source

Evaluating Public Behavior toward Antibiotic Use in Riyadh: A Cross-Sectional Study

Pharmacoepidemiology
Background: Antibiotic resistance presents a global challenge. Community awareness of antibiotic use has not been studied extensively in Saudi Arabia. This study aimed to assess public awareness of the appropriate use and indications of antibiotics in ...
Sarah A. Alfagih, Monirah A. Albabtain, Muaath Alfagih, Nouf Alharbi   +3 more
doaj   +1 more source

Pharmacovigilance and pharmacoepidemiology

, 2001
Pharmacovigilance involves the detection of unexpected, and often undesirable, adverse effects of drugs. Pharmacoepidemiology, often considered a sub-domain in pharmacovigilance, attempts to quantify the frequency of these adverse effects, and to ...
De Vries, Corinne, De Jong-Van Den Berg, Lolkje   +1 more
core   +1 more source

The promotion of data sharing in pharmacoepidemiology [PDF]

, 2014
This article addresses the role of pharmacoepidemiology in patient safety and the crucial role of data sharing in ensuring that such activities occur. Against the backdrop of proposed reforms of European data protection legislation, it considers whether ...
Sethi, Nayha
core   +1 more source

National clinical audits as distributed diabetes surveillance infrastructure: Consensus lessons from Ireland

Diabetic Medicine, EarlyView.
Ireland's national clinical audits capture valuable but fragmented diabetes‐related intelligence across paediatric diabetes, cardiovascular disease, critical care, stroke, hip fracture and hospital mortality. Abstract Background Diabetes increasingly shapes acute‐care demand through cardiovascular disease, critical illness, frailty, stroke and ...
Seif El Hadidi, Sean F. Dinneen, Gintare Valentelyte, Lauren Churchill, Nuala P. Murphy, Karina Hamilton, Edward W. Gregg   +6 more
wiley   +1 more source

“My Addiction Doesn’t Define Me”—Experiences of Stigma among Mothers with Opioid Use Disorder

Pharmacoepidemiology
Opioid use in women has increased by 300% since 1999, and opioid use disorder among pregnant women has quadrupled. The stigma of substance use disorder is a significant barrier to treatment, especially among women.
Christine Bakos-Block, Andrea Yatsco, A. Sarah Cohen, Francine Vega, Tiffany Champagne-Langabeer   +4 more
doaj   +1 more source

Tirzepatide Use Resulted in Clinically Meaningful Weight Reduction in Individuals With Obesity or Overweight: 12‐Month Real‐World Results

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study assessed the real‐world effectiveness of tirzepatide in commercially insured individuals without diabetes, eligible for obesity medications (OMs), including glucagon like‐peptide‐1 receptor agonist (GLP‐1 RA)‐naïve individuals (i.e., no GLP‐1 RA prescription during the 12‐month pre‐index period) and GLP‐1 RA‐experienced ...
Chanadda Chinthammit, Theresa Hunter Gibble, Melody Dehghan, Donna Mojdami, Ahong Huang, David Schapiro, Harold Bays   +6 more
wiley   +1 more source