Results 241 to 250 of about 30,618 (276)
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Depression and Pharmacogenetics
Archives of Psychiatric Nursing, 2018Depression is the most common and leading devastating psychiatric illness that affects a majority of the world population. The treatment of depression has been a challenge for a majority of patients and healthcare practitioners. The advent of pharmacogenomics (PGx) empowered the Food and Drug Administration to approve some antidepressant biomarkers for
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Current Protocols in Pharmacology, 2003
AbstractPharmacogenetics is the study of relationships between genetic variation and inter‐individual differences of drug response. As the field has matured over the past 15 years, a remarkable diversity of pathways, variation types, and mechanisms have been found to be relevant pharmacogenetic factors.
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AbstractPharmacogenetics is the study of relationships between genetic variation and inter‐individual differences of drug response. As the field has matured over the past 15 years, a remarkable diversity of pathways, variation types, and mechanisms have been found to be relevant pharmacogenetic factors.
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[Pharmacogenetics of immunosuppressants].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2015Individualized drug therapy with immunosuppressants is an hot topic in transplantation. Therapeutic drug monitoring (TDM) is currently utilized to guide therapy, but toxic or subtherapeutic concentrations can only be identified after the drug is administered.
Cojutti P. G., Baraldo M.
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Pharmacogenetics and Psychiatry
Current Psychiatry Reports, 2004Genetic factors play a significant role in predicting an individual's response to a drug. The response may be the desired therapeutic effect of the drug and also may be the undesirable development of adverse effects. This relationship between genes and drug response interests the pharmacogeneticist. This article aims to give an overview of the exciting
Basu, A, Tsapakis, E, Aitchison, K
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Pharmacogenetics and psychopharmacotherapy
Journal of Clinical Pharmacy and Therapeutics, 2000Response to drugs can vary between individuals and between different ethnic populations. The biological (age, gender, disease and genetics), cultural and environmental factors which contribute to these variations are considered in this review. The most important aspect is the genetic variability between individuals in their ability to metabolize drugs ...
N, Poolsup, A, Li Wan Po, T L, Knight
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Drug News & Perspectives, 2003
Pharmacogenetics uses genetic information to tailor drug treatment to the individual, maximizing clinical response and minimizing side effects. Failure to respond to medication and adverse side effects are common problems in psychiatry. Intolerable side effects can lead to discontinuation of medication. Individual genetic differences can determine both
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Pharmacogenetics uses genetic information to tailor drug treatment to the individual, maximizing clinical response and minimizing side effects. Failure to respond to medication and adverse side effects are common problems in psychiatry. Intolerable side effects can lead to discontinuation of medication. Individual genetic differences can determine both
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Personalized Medicine, 2006
The taxanes paclitaxel and docetaxel exert their anticancer activity by stabilizing microtubules during cell division. There is significant interindividual variability in response and toxicity between paclitaxel and docetaxel. Interpatient variability also exists for response and toxicity from each drug.
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The taxanes paclitaxel and docetaxel exert their anticancer activity by stabilizing microtubules during cell division. There is significant interindividual variability in response and toxicity between paclitaxel and docetaxel. Interpatient variability also exists for response and toxicity from each drug.
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