Results 171 to 180 of about 222,667 (349)

Population Pharmacokinetic Parameters of Valproic Acid; Conventional and Slow Release Formulation.

open access: bronze, 1998
Koji Tanikawa   +7 more
openalex   +2 more sources

Relationship of Hepatic Functional Imaging to Irinotecan Pharmacokinetics and Genetic Parameters of Drug Elimination [PDF]

open access: bronze, 2006
Michael Michael   +14 more
openalex   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li   +15 more
wiley   +1 more source

Association between Vancomycin Pharmacokinetic Parameters and Clinical and Microbiological Efficacy in a Cohort of Neonatal Patients. [PDF]

open access: yesAntimicrob Agents Chemother, 2022
Mejías-Trueba M   +7 more
europepmc   +1 more source

Pharmacokinetics and oxidation parameters in volunteers supplemented with microencapsulated docosahexaenoic acid

open access: green, 2018
YuriyK Bashmakov   +6 more
openalex   +2 more sources

A limited sampling strategy to estimate individual pharmacokinetic parameters of methotrexate in children with acute lymphoblastic leukemia [PDF]

open access: bronze, 2007
Christine Plard   +6 more
openalex   +1 more source

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

open access: yesAdvanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang   +17 more
wiley   +1 more source

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