Results 221 to 230 of about 222,667 (349)

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

The Association Between Genetic Polymorphisms of <i>UGT1A1</i>, <i>ABCG2</i>, and <i>NR1I2</i> and Dolutegravir Pharmacokinetic Parameters in Thai People Living with HIV. [PDF]

Pharmaceutics
Chanruang A, Birnbaum AK, Sirilun S, Chupradit S, Ubolyam S, Hiranburana N, Cho YS, Shin JG, Avihingsanon A, Punyawudho B.   +9 more
europepmc   +1 more source

An automated approach to identify scientific publications reporting pharmacokinetic parameters. [PDF]

Wellcome Open Res, 2021
Gonzalez Hernandez F, Carter SJ, Iso-Sipilä J, Goldsmith P, Almousa AA, Gastine S, Lilaonitkul W, Kloprogge F, Standing JF.   +8 more
europepmc   +1 more source

Parameters sensitivity of pharmacokinetics model parameters

Симпозиум «Математическое моделирование и высокопроизводительные вычисления в биоинформатике, биомедицине и биотехнологии», 2018
openaire   +1 more source

The pharmacokinetic parameters (mean±SD, n = 6) of gamithromycin in serum, transudate, and exudate after i.v administration of 6 mg/kg.

Qingwen Yang (119119), Xuesong Liu (614293), Yongzhi Lv (21446181), Yushen Li (21446184)   +3 more
openalex   +1 more source

INVIVO EVALUATION OF THE EFFECTS OF Allium sativum ON THE PHARMACOKINETIC PARAMETERS OF CIPROFLOXACIN AND ISONIAZID.

, 2012
Sunday Odunke Nduka, OKONTA JM, Charles Okechukwu Esimone   +2 more
openalex   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu, Haozhe Ren, Hua Li, Jinghan Zhao, Miaomiao Cao, Tian Tang, Youbei Qiao, Liting Chen, Tiehong Yang, Hong Wu   +9 more
wiley   +1 more source

PROTAC-DB 3.0: an updated database of PROTACs with extended pharmacokinetic parameters. [PDF]

Nucleic Acids Res
Ge J, Li S, Weng G, Wang H, Fang M, Sun H, Deng Y, Hsieh CY, Li D, Hou T.   +9 more
europepmc   +1 more source

Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the open-source R package mapbayr. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2021
Le Louedec F, Puisset F, Thomas F, Chatelut É, White-Koning M.   +4 more
europepmc   +1 more source

Extended‐release antiepileptic drugs: A comparison of pharmacokinetic parameters relative to original immediate‐release formulations [PDF]

, 2012
Ilo E. Leppik, Collin A. Hovinga
openalex   +1 more source