Journal of Venomous Animals and Toxins including Tropical Diseases, 2012 The purpose of the present study was to investigate the biodistribution profile of the venom of Hemiscorpius lepturus, the most dangerous scorpion in Iran.
R Seyedian +4 more
doaj +1 more source
Chromatographic lipophilicity and pharmacokinetic behavior of some newly synthesized styryl lactone stereoisomers [PDF]
Acta Periodica Technologica, 2017 The RP-HPLC retention constants of several newly synthesized cytotoxic styryl lactone stereoisomers were determined as parameters of their lipophilicity.
Lоnčаr Dаvоr М. +5 more
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Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats [PDF]
, 2017 The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in ...
Beaudry, F +6 more
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Pharmaceutical Biology, 2017 Context: Chlorogenic acid (ChA) is the major compound in Shuang-Huang-Lian (SHL), which is mainly composed of ChA, baicalin, and Forsythia suspense Thunb Vahl.
Rong Liu, Ke Lai, Yu Xiao, Jing Ren
doaj +1 more source
Application of a single-objective, hybrid genetic algorithm approach to pharmacokinetic model building. [PDF]
, 2012 A limitation in traditional stepwise population pharmacokinetic model building is the difficulty in handling interactions between model components. To address this issue, a method was previously introduced which couples NONMEM parameter estimation and ...
Belani, Chandra P +12 more
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Ukrainian Journal of Veterinary Sciences, 2021 The article presents the results of studies of the effect of fenbenzyl and fenbendazole on the antioxidant status in dogs under the experimental infection with a causative agent of toxocariasis.
V. V. STYBEL +7 more
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Pharmacokinetics of recombinant human erythropoietin applied subcutaneously to children with chronic renal failure [PDF]
, 1993 The single-dose pharmacokinetics of recombinant human erythropoietin (rHuEPO) given SC was investigated in 20 patients aged 7-20 years at different stages of chronic renal failure.
Braun, A. +5 more
core +1 more source
Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]
, 2015 Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne +9 more
core +4 more sources
Bioequivalence Study of Two Long-Acting Formulations of Oxytetracycline Following Intramuscular Administration in Bovines [PDF]
, 2016 The aim of this study was to evaluate the bioequivalence of two commercial long-acting formulations based on oxytetracycline (OTC) hydrochloride between the reference formulation (Terramycin LA, Pfizer) and a test formulation (Cyamicin LA, Fort Dodge ...
Fernandez Lastra, Cecilia +7 more
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Pharmaceutics, 2023 The search for new drugs is an extremely time-consuming and expensive endeavour. Much of that time and money go into generating predictive human pharmacokinetic profiles from preclinical efficacy and safety animal data. These pharmacokinetic profiles are
Tridib Chaira +2 more
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