Results 251 to 260 of about 496,699 (309)
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Diabetes Care, 1984
Where adjustments of diet, physical activity, and dosage of insulin are well known to diabetologists and diabetic patients, present-day knowledge of factors of importance to the pharmacokinetics of insulin is frequently ignored. The pharmacokinetics of insulin comprise the absorption process, the distribution including binding to circulating insulin ...
Binder, C +3 more
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Where adjustments of diet, physical activity, and dosage of insulin are well known to diabetologists and diabetic patients, present-day knowledge of factors of importance to the pharmacokinetics of insulin is frequently ignored. The pharmacokinetics of insulin comprise the absorption process, the distribution including binding to circulating insulin ...
Binder, C +3 more
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An Overview on Pharmacokinetics and Pharmacokinetic Modeling
Asian Journal of Research in Pharmaceutical Science, 2020Pharmacokinetics is proposed to study the absorption, distribution, biotransformation and elimination of drugs in man and animals. A more careful description of the data can be obtained interpolating and extrapolating the drug concentrations with some mathematical functions.
Subhashis Debnath, T. H. Harish Kumar
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Pharmacokinetics of Teicoplanin
Chemotherapy, 1988We investigated the pharmacokinetic properties of teicoplanin, after 200 mg i.v. and i.m. administration in 10 healthy male subjects by assuming a three-compartment open model with elimination from the central compartment. The mean peak plasma level was 7.16 micrograms/ml reached after 2.26 h.
RIPA, Sandro +3 more
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Pharmacokinetics of ceftizoxime
European Journal of Clinical Pharmacology, 1985The kinetics of ceftizoxime, a newly developed cephalosporin, were evaluated in 6 healthy subjects, with respect to its excretory pathways especially by the biliary route. Total, renal and biliary clearance were determined at two different steady states.
U, Gundert-Remy +3 more
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International Journal of Gynecology & Obstetrics, 1990
The main types of pharmacologic therapy used to treat the hormone deficiency of menopause are parenteral and oral administrations of estrogen. Parenteral administration results in predictable absorption without major intermediary metabolism, whereas all oral estrogens are subject to intestinal metabolism before entering the systemic circulation ...
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The main types of pharmacologic therapy used to treat the hormone deficiency of menopause are parenteral and oral administrations of estrogen. Parenteral administration results in predictable absorption without major intermediary metabolism, whereas all oral estrogens are subject to intestinal metabolism before entering the systemic circulation ...
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Pharmacokinetics and Immunotoxicity
1980The possibilities of different actions of xenobiotics on the immunological system are described (different cells with immunocompetence in distinct stages of development, indirect action, pharmacokinetics and especially biotransformation). Results concerning the toxic action and biotransformation are given for DOTC. The atrophy of the thymus produced by
P, Lange, G, Hennighausen, U, Karnstedt
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The Pharmacokinetics of the Kininogens
Thrombosis Research, 1998Recent evidence has shown that plasma high molecular weight kininogen and both kininogens have the ability to modulate prekallikrein activation and thrombin-induced platelet activation, respectively. However, nothing is known about the plasma clearance and tissue distribution of these proteins.
A H, Schmaier +3 more
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The American Journal of Medicine, 1986
The pharmacokinetics of terazosin have been assessed in human volunteers, hypertensive patients, a limited number of elderly volunteers, and a small number of patients with congestive heart failure. Terazosin was administered intravenously and orally in doses ranging up to 7.5 mg.
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The pharmacokinetics of terazosin have been assessed in human volunteers, hypertensive patients, a limited number of elderly volunteers, and a small number of patients with congestive heart failure. Terazosin was administered intravenously and orally in doses ranging up to 7.5 mg.
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Pharmacokinetics of the Taxanes
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1997The pharmacokinetics of the taxanes paclitaxel and docetaxel have been studied extensively in humans. Paclitaxel has distinctly nonlinear pharmacokinetics, with saturable distribution and elimination features. Docetaxel pharmacokinetics are well described by linear processes, although some investigators detected subtle nonlinear characteristics ...
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Pharmacokinetics of prostaglandins
Best Practice & Research Clinical Obstetrics & Gynaecology, 2003Naturally occurring prostaglandins (PGs) are rapidly metabolized in the human circulation. For clinical use a number of PG analogues have therefore been developed which are resistant to rapid inactivation. Among these are carboprost, gemeprost and misoprostol.
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