Results 1 to 10 of about 1,582,171 (351)
mSphere, 2016 The urgent need to develop new antimicrobial therapies has spawned the development of repurposing screens in which well-studied drugs and other types of compounds are tested for potential off-label uses.
Ashley J. Dittmar +2 more
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Cluster Headache and Hypoxia: Breathing New Life into an Old Theory, with Novel Implications
Neurology InternationalCluster headache is a severe, poorly understood disorder for which there are as yet virtually no rationally derived treatments. Here, Lee Kudrow’s 1983 theory, that cluster headache is an overly zealous response to hypoxia, is updated according to ...
Jonathan M. Borkum
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Chiral drugs : one drug or two? : Clinical pharmacology through the looking glass : reflections on the racemate vs enantiomer debate [PDF]
, 1994 Most of the synthetic chiral agents administered as drugs are still marketed as racemic mixtures. Such drug enantiomers can differ substantially in their pharmacological, pharmacokinetic and toxic properties.
Mifsud, Janet
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Development perspectives of new generation medications based on the redox system regulators [PDF]
, 2016 This survey paper describes the necessity of the development of new medications influencing the body redox-potential. It supports the most pressing branch of pharmacology, which coincides with logically relevant attempts to shift paradigm of pharmacology
Galenko-Yaroshevsky, P. A. +3 more
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Veterinary Pharmacology: Is it Still Pharmacology’s Cinderella? [PDF]
Clinical and Experimental Pharmacology, 2012 n ...
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Interaction between IP, TP, and 5-HT2 receptors during contractions to prostacyclin in rat renal arteries [PDF]
, 2015 Conference Theme: Tomorrow’s medicines: pharmacology, patients and populationspublished_or_final_versionConference Theme: Tomorrow's medicines: pharmacology, patients and ...
Baretella, OM, Vanhoutte, PMGR, Xu, A
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Nicotine : Pharmacology and therapeutic implications in neurodegenerative and psychiatric disorders [PDF]
, 2005 The pathophysiology of tobacco-related diseases is complex and multifactorial. Among the various compounds in tobacco smoke are carcinogens such as nitrosamines, irritants such as a variety of phenolic compounds, volatiles such as carbon monoxide, and of
Scerri, Charles
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Statistics in Pharmacology [PDF]
British Journal of Pharmacology, 2007 Statistics is an important tool in pharmacological research that is used to summarize (descriptive statistics) experimental data in terms of central tendency (mean or median) and variance (standard deviation, standard error of the mean, confidence interval or range) but more importantly it enables us to conduct hypothesis testing. This is of particular
openaire +3 more sources
The Famous Poisonings in History
Swiss Journal of Radiology and Nuclear MedicineThe use of poisons spans human history, serving as tools for war, execution, assassination, revenge, and political control. Ancient texts like the "Rig Veda" mention poisoned weapons, and many civilizations used natural toxins—such as frog skin, snake ...
Arturo J. Brugger Aubán
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Drugs, 1994 (+/-)-Tramadol is a central analgesic with low affinity for opioid receptors. The rate of production of its M1 metabolite (O-demethyl tramadol) is influenced by debrisoquine-type polymorphism, and this metabolite shows a higher affinity for opioid receptors than the parent drug.
Dayer, P +2 more
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