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History and Future Perspectives on the Discipline of Quantitative Systems Pharmacology Modeling and Its Applications [PDF]
Frontiers in Physiology, 2021 Mathematical biology and pharmacology models have a long and rich history in the fields of medicine and physiology, impacting our understanding of disease mechanisms and the development of novel therapeutics.
Benedetto Piccoli +2 more
exaly +3 more sources
Iraqi Journal of Pharmaceutical Sciences, 2023 Cyclophosphamide (CP) is a cytotoxic alkylating agent it's used associated with different side effects including lung toxicity. Vitamin B2 and vitamin B12 have lung-protective effects.
waleed khalid ghanim +2 more
doaj +1 more source
Acknowledgment to the Reviewers of Future Pharmacology in 2022
Future Pharmacology, 2023 High-quality academic publishing is built on rigorous peer review [...]
Future Pharmacology Editorial Office
doaj +1 more source
Language as a Window Into the Altered State of Consciousness Elicited by Psychedelic Drugs
Frontiers in Pharmacology, 2022 Psychedelics are drugs capable of eliciting profound alterations in the subjective experience of the users, sometimes with long-lasting consequences.
Enzo Tagliazucchi, Enzo Tagliazucchi
doaj +1 more source
Application of Quantitative Systems Pharmacology to guide the optimal dosing of COVID-19 vaccines [PDF]
CPT: Pharmacometrics and Systems Pharmacology, 2021, 2021 Optimal use and distribution of Covid-19 vaccines involves adjustments of dosing. Due to the rapidly-evolving pandemic, such adjustments often need to be introduced before full efficacy data are available. As demonstrated in other areas of drug development, quantitative systems pharmacology (QSP) is well placed to guide such extrapolation in a rational
arxiv +1 more source
Frontiers in Pharmacology, 2021 Ethnopharmacology relevance: Yunnan Baiyao (YNBY), a traditional Chinese medicine formulae, has some significant properties including activating blood circulation to dissipate blood stasis (Huo-Xue-Hua-Yu), eliminating swelling and alleviating pain (Xiao-
Qi Yao +10 more
doaj +1 more source
Repression of the stress granule protein G3BP2 inhibits immune checkpoint molecule PD‐L1
Molecular Oncology, EarlyView., 2022 Mounting evidence suggests that cancer stemness and immunosuppression are related, but the underlying mechanisms are not clear. We previously reported that the stress granule‐associated protein G3BP2 is involved in regulating tumor‐initiating (stem) cells.
Yanhong Zhang +3 more
wiley +1 more source
Frontiers in Public Health, 2022 With the continuous development of information technology, new teaching resources “micro-video class” and teaching model “flipped classroom” have gradually attracted the attention of teachers.
Yi-Ying Wu +7 more
doaj +1 more source
Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance
Molecular Oncology, EarlyView., 2023 Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela +2 more
wiley +1 more source
Pharmacology of antihistamines [PDF]
Indian Journal of Dermatology, 2011 H1-antihistamines, the mainstay of treatment for urticaria, were developed from anticholinergic drugs more than 70 years ago. They act as inverse agonists rather than antagonists of histamine H1-receptors which are members of the G-protein family.
Martin K. Church +3 more
openaire +8 more sources