Results 121 to 130 of about 444,964 (236)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Optimizing Intrathecal Opioid Strategies for Cesarean Section: A Comprehensive Narrative Review of Pharmacology, Clinical Outcomes, and Safety. [PDF]

Cureus
Moisa RC, Negrut N, Botea MO, Bodog TM, Moisa CCM, Thomas TC, John HT.   +6 more
europepmc   +1 more source

Cannabinoids and gastrointestinal motility: Pharmacology, clinical effects, and potential therapeutics in humans. [PDF]

Neurogastroenterol Motil, 2018
Camilleri M.
europepmc   +1 more source

Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this study, we analyzed biomarkers of neuronal, glial, and vascular injury in longitudinal paired samples of blood and cerebrospinal fluid after prophylactic cranial irradiation in patients with small cell lung cancer. Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) increased in serum and cerebrospinal ...
Erik Fernström, Thomas Björk‐Eriksson, Pontus Erickson, Jan Nyman, Henrik Zetterberg, Marie Kalm   +5 more
wiley   +1 more source

Fenoldopam for Renal Protection in Cardiac Surgery: Pharmacology, Clinical Applications, and Evolving Perspectives. [PDF]

J Clin Med
Cuttone G, La Via L, Misseri G, Geraci G, Sorbello M, Pappalardo F.   +5 more
europepmc   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

The Rise of Remimazolam: A Review of Pharmacology, Clinical Efficacy, and Safety Profiles. [PDF]

Cureus
Dessai S, Ninave S, Bele A.
europepmc   +1 more source

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Botanical characterization, phytochemistry, biosynthesis, pharmacology clinical application, and breeding techniques of the Chinese herbal medicine Fritillaria unibracteata. [PDF]

Front Pharmacol
Zhang Y, Han H, Li D, Fan Y, Liu M, Ren H, Liu L.   +6 more
europepmc   +1 more source

Methamphetamine: an update on epidemiology, pharmacology, clinical phenomenology, and treatment literature. [PDF]

Drug Alcohol Depend, 2014
Courtney KE, Ray LA.
europepmc   +1 more source