Results 121 to 130 of about 898,450 (282)

E-liquid flavor alters nicotine exposure, puff topography, and subjective effects under ad libitum use conditions

Addictive Behaviors Reports
Introduction: Electronic nicotine delivery systems (ENDS) are most often used with e-liquids having fruit, and menthol or mint flavor, with tobacco flavor being least prevalent.
Arit M. Harvanko, Conor A. Ruzycki, Jacob McDonald, Eric D. Claus, Megan Schroeder, Carolina Ramôa   +5 more
doaj   +1 more source

Old School Catalog 1916-17, Chicago College of Medicine and Surgery [PDF]

, 1916
https://scholar.valpo.edu/oldschoolcatalogs/1104/thumbnail ...
Valparaiso University
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Response to: “Challenges in DPYD Test Implementation in Patients Treated with Fluoropyirimidines, is DPYD Genotype Arriving on Time?” [Response to Letter]

Pharmacogenomics and Personalized Medicine
Cristina Montrasio,1 Stefania Cheli,1 Emilio Clementi2,3 1Unit of Clinical Pharmacology, ASST Fatebenefratelli Sacco, L. Sacco University Hospital, Milan, Italy; 2Clinical Pharmacology Unit, Department of Biomedical and Clinical Sciences, L.
Montrasio C, Cheli S, Clementi E
doaj  

Advancing the utilization of real‐world data and real‐world evidence in clinical pharmacology and translational research—Proceedings from the ASCPT 2023 preconference workshop

Clinical and Translational Science
Real‐world data (RWD) and real‐world evidence (RWE) are now being routinely used in epidemiology, clinical practice, and post‐approval regulatory decisions.
Jing Liu, Karen Rowland‐Yeo, Almut Winterstein, Simon Dagenais, Qi Liu, Jeffrey S. Barrett, Rui Zhu, Cyrus Ghobadi, Amita Datta‐Mannan, Joy Hsu, Sujatha Menon, Mariam Ahmed, Pooja Manchandani, Paulien Ravenstijn   +13 more
doaj   +1 more source

A Comprehensive Review of the Chemistry, Pharmacokinetics, Pharmacology, Clinical Applications, Adverse Events, and Quality Control of Indigo Naturalis. [PDF]

Front Pharmacol, 2021
Sun Q, Leng J, Tang L, Wang L, Fu C.
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Pharmacology, Clinical Effects, and Therapeutic Potential of Cannabinoids for Gastrointestinal and Liver Diseases. [PDF]

Clin Gastroenterol Hepatol, 2021
Maselli DB, Camilleri M.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Cardiovascular safety pharmacology: beyond arrhythmic risk assessment

Frontiers in Cardiovascular Medicine
Cardiovascular safety pharmacology arose from the need to assess certain forms of drug induced functional cardiotoxicity in toxicology within a regulatory framework.
Raafat Fares, Pascal Champéroux
doaj   +1 more source