Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan+4 more
wiley +1 more source
Brivaracetam: Pharmacology, Clinical Efficacy, and Safety in Epilepsy. [PDF]
Hwang H, Kim WJ.
europepmc +1 more source
Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels
A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco+12 more
wiley +1 more source
Optimizing Intrathecal Opioid Strategies for Cesarean Section: A Comprehensive Narrative Review of Pharmacology, Clinical Outcomes, and Safety. [PDF]
Moisa RC+6 more
europepmc +1 more source
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao+5 more
wiley +1 more source
Fenoldopam for Renal Protection in Cardiac Surgery: Pharmacology, Clinical Applications, and Evolving Perspectives. [PDF]
Cuttone G+5 more
europepmc +1 more source
Cannabinoids and gastrointestinal motility: Pharmacology, clinical effects, and potential therapeutics in humans. [PDF]
Camilleri M.
europepmc +1 more source
Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li+11 more
wiley +1 more source
Glucocorticoids Do Not Affect the Vascular Component of TRP-Mediated Neurogenic Skin Inflammation
Heleen Marynissen, Jan de Hoon Center for Clinical Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, BelgiumCorrespondence: Heleen Marynissen, Center for Clinical Pharmacology, Department of Pharmaceutical and ...
Marynissen H, de Hoon J
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