Results 191 to 200 of about 839,683 (307)

Cannabinoids and gastrointestinal motility: Pharmacology, clinical effects, and potential therapeutics in humans. [PDF]

Neurogastroenterol Motil, 2018
Camilleri M.
europepmc   +1 more source

HGF/c‐Met Axis‐Targeted Nanotherapy via GSH‐Responsive Polymer Platforms Suppresses Uveal Melanoma Metastasis

Advanced Healthcare Materials, EarlyView.
To suppress uveal melanoma metastasis (UM), the GSH‐responsive polymer named NP@Oxa/Criz has been successfully prepared. NP@Oxa/Criz selectively accumulates in UM tumors, targeting HGF/c‐Met Axis to undermine the stemness and metastasis of UM while triggering immunogenic cell death through DAMPs release to boost anti‐tumor immunity.
Hui Tao, Hanhan Liu, Hanchen Zhang, Hong Ren, Binyu Wen, Jing Zhang, Jiaqi Du, Ziyi Cai, Zhihong Deng   +8 more
wiley   +1 more source

The Rise of Remimazolam: A Review of Pharmacology, Clinical Efficacy, and Safety Profiles. [PDF]

Cureus
Dessai S, Ninave S, Bele A.
europepmc   +1 more source

Methamphetamine: an update on epidemiology, pharmacology, clinical phenomenology, and treatment literature. [PDF]

Drug Alcohol Depend, 2014
Courtney KE, Ray LA.
europepmc   +1 more source

A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals

Advanced Healthcare Materials, EarlyView.
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin, Kyungtae Kim, Jaeseung Lee, Johyeon Nam, Eunha Baeg, Chaeyeon You, Hanseul Choi, Minji Kim, Chun Kee Chung, Jae Geun Kim, Jong Hyun Ahn, Miryung Han, Jibum Kim, Sungchil Yang, Sung Q Lee, Sunggu Yang   +15 more
wiley   +1 more source

Glucocorticoids Do Not Affect the Vascular Component of TRP-Mediated Neurogenic Skin Inflammation

Journal of Inflammation Research
Heleen Marynissen, Jan de Hoon Center for Clinical Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, BelgiumCorrespondence: Heleen Marynissen, Center for Clinical Pharmacology, Department of Pharmaceutical and ...
Marynissen H, de Hoon J
doaj  

Botanical characterization, phytochemistry, biosynthesis, pharmacology clinical application, and breeding techniques of the Chinese herbal medicine Fritillaria unibracteata. [PDF]

Front Pharmacol
Zhang Y, Han H, Li D, Fan Y, Liu M, Ren H, Liu L.   +6 more
europepmc   +1 more source

Engineered Chitosan‐Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons

Advanced Healthcare Materials, EarlyView.
This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer, Adriana Vilaça, Miguel Xavier, Rafael Santos, Ariel Ionescu, María Lázaro, Victoria Leiro, Eran Perlson, Sofia C. Guimarães, Ben M. Maoz, Ana P. Pêgo   +10 more
wiley   +1 more source

A Canadian Perspective

PLoS Medicine, 2005
Till James E
doaj   +1 more source

Armeniacae semen amarum: a review on its botany, phytochemistry, pharmacology, clinical application, toxicology and pharmacokinetics. [PDF]

Front Pharmacol
Tang S, Wang M, Peng Y, Liang Y, Lei J, Tao Q, Ming T, Shen Y, Zhang C, Guo J, Xu H.   +10 more
europepmc   +1 more source