Results 221 to 230 of about 858,870 (284)

Inflammatory Bowel Disease (IBD): Clinical Diagnosis and Treatment. [PDF]

J Clin Med
Silva I, da Silva MTB.
europepmc   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

Advanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba, Giulia Puliatti, Domenica Donatella Li Puma, Bruno Bandiera, Beatrice Cannata, Maria Elena Marcocci, Nicolina Castagno, Irene Contento, Salvatore Impemba, Mariarosa Scognamiglio, Rocco Di Girolamo, Vincenzo Naddeo, Patrizia Canton, Carmine Capacchione, Laura Sposito, Martina Albini, Francesco Pastore, Silvia Baroni, Alfonso Grassi, Claudio Grassi, Roberto Piacentini   +20 more
wiley   +1 more source

Citrate‐Enhanced PCL Scaffolds for Bone Tissue Engineering

Advanced Materials Interfaces, EarlyView.
This study investigates citrate‐enhanced polycaprolactone (PCL) scaffolds designed for bone tissue engineering. Utilizing 3D printing technology, four scaffold patterns (triple hexagon, grid, gyroid, zigzag) are evaluated for mechanical properties, cellular proliferation, osteogenic differentiation, and gene expression.
Muge Musmula, Oguz Sogut, Basak Aru, Gizem Gurel, Serdar Sezer, Gulderen Yanıkkaya Demirel, Umran Aydemir Sezer   +6 more
wiley   +1 more source

Human-Based Technologies in Cardiovascular Pharmacology Research. [PDF]

J Cardiovasc Pharmacol
Biondi-Zoccai G, Frati G, Carnevale R, Booz GW.   +3 more
europepmc   +1 more source

An Anti‐Myd88 Peptide Synergistically Enhances the Anti‐Inflammatory Effects of Extracellular Vesicles from Naïve Umbilical Cord MSC or HEK293F CD24 Overexpressing Cells

Advanced Materials Interfaces, EarlyView.
This study confirms that extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) or HEK293F cells overexpressing CD24 have anti‐inflammatory effects in macrophages and monocytes. Further loading either of these EVs with an anti‐Myd88 peptide synergistically enhanced the anti‐inflammatory effects of the EVs.
Burçin İrem Abas, Markus Bergqvist, Lijuan Yu, Yi Wang, Mario Gimona, Kyong‐su Park, Jan Lötvall   +6 more
wiley   +1 more source

Bridging academia and industry: advancing systems biology and QSP education through AstraZeneca's collaborative partnerships. [PDF]

Front Syst Biol
Pichardo-Almarza C, Kimko H.
europepmc   +1 more source

A Modular, Lego‐Like Microfluidic Platform for Multimodal Analysis of Biofilm Formation and Antimicrobial Response

Advanced Materials Interfaces, EarlyView.
A modular microfluidic platform with integrated electrodes enables real‐time, label‐free monitoring of biofilm formation, treatment, and regrowth. The system evaluates both antibiotic response and antimicrobial coating efficacy on P. aeruginosa. Its LEGO‐like design supports dynamic migration studies, offering a clinically relevant, scalable tool for ...
Deema Islayem, Sagar Arya, Nabila Yasmeen, Nicholas Hallfors, Huu Ngoc, Sara Alkhatib, Ioanna Mela, Siddiq Anwar, Vi Khanh Truong, Anna Maria Pappa   +9 more
wiley   +1 more source

Mental health disorders among people living with HIV in sub-Saharan Africa: a scoping review protocol. [PDF]

BMJ Open
Adedeji WA, Ishola AG, Elugbadebo O, Oladepo OM, Mudzviti T, Kaiyo-Utete M, Willis N, Adebayo DA, Mtisi TJ, Chokuona KFV, Ma Q, Cha R, Hutson A, Charurat ME, Yusuf OB, Maponga C, Fehintola FA, Gureje O, Morse GD.   +18 more
europepmc   +1 more source

Bioengineered Models of Nerve Regeneration

Advanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson, John Paul Frampton   +1 more
wiley   +1 more source

Clinical pharmacology of thiopropium bromide

Терапевтический архив, 2003
A N Tsoi, V V Arkhipov
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