A Reflection on the Evolution of Antibody-Based Therapies in Oncology: Trastuzumab as an Exemplar-Commentary on Dijkers et al. [PDF]
Holstein SA.
europepmc +1 more source
Vertical Membrane‐Free Organ‐on‐a‐Chip for High‐Throughput In Vitro Studies and Drug Screening
This novel microfluidic organ‐on‐a‐chip (OoC) platform enables cost‐effective, high‐throughput in vitro modeling. With vertical compartmentalization and gravity‐driven flow, it eliminates porous membranes and external pumps. Successfully generating intestine, cartilage, and tendon models, this study demonstrates drug responses, including 5‐fluorouracil
Xavier Barceló+5 more
wiley +1 more source
Unexpected Falsely High Vancomycin Concentrations in a Patient with Endocarditis During Routine Therapeutic Drug Monitoring. [PDF]
Galán-Caballero L+6 more
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Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen+3 more
wiley +1 more source
Correction: Mechanism underlying the involvement of CXCR4/CXCL12 in diabetic wound healing and prospects for responsive hydrogel-loaded CXCR4 formulations. [PDF]
Wang L, Nie F, Lu Z, Chong Y.
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Liquiritin enhances the osteogenic differentiation of BMSCs and promotes fracture healing through the activation of the ERK/JNK signaling pathway and by exerting antioxidant protective effects. Abstract Liquiritin, a flavonoid from Glycyrrhiza uralensis L., has diverse pharmacological properties, but its impact on fracture healing is unexplored.
Haijun Mao+6 more
wiley +1 more source
Correction: Clinical pharmacist-led problem-specific education as a strategy for addressing suboptimal antimicrobial use in intensive care unit: a prospective pre-post analysis. [PDF]
İlerler EE+4 more
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Transcranial photobiomodulation (PBM) enhances spatial working memory in healthy rats under both continuous and alternating stimulation protocols. At the neural level, PBM modulates cytochrome c oxidase activity, increases prefrontal and hippocampal synaptic markers, and induces region‐specific c‐Fos expression. These effects suggest improved cognitive
Candela Zorzo+6 more
wiley +1 more source
Classrooms to Clinics: A Capstone Preclinical Course Designed from Educational, Social, and Developmental Perspectives on the Transition to Clerkship. [PDF]
Worden MK, Bray MJ.
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