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Clinical pharmacology in Nigeria
Clinical Pharmacology & Therapeutics, 1974Nigeria, today, with a strongly developing economy, is laying the fQUndation for future achievement. While there is no specific unit of clinical pharmacology yet in the country, the principle is recognized and the need appreciated. There are many features in Nigeria that, if properly appreciated and utilized, will aid the progression of clinical ...
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Clinical Pharmacology of Digoxin
Pediatric Clinics of North America, 1972Although digoxin is invaluable for a variety of cardiovascular diseases, and it is virtually the only cardiac glycoside in common use today in children and infants, it is known to have a low margin of safety. A central goal of this paper is to aid the education of clinicians so as to alter a traditional mode of administering digoxin, that of pushing to
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Clinical Pharmacology of Lacidipine
Journal of Cardiovascular Pharmacology, 1991The safety and tolerability of lacidipine was assessed in a volunteer population, and its pharmacodynamic and pharmacokinetic profiles evaluated. In normotensive subjects, single oral doses of 3-5 mg of lacidipine produced a dose-related fall in peripheral vascular resistance.
S T, Hall +4 more
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Clinical pharmacology of thalidomide
European Journal of Clinical Pharmacology, 2001Thalidomide has a chiral centre, and the racemate of (R)- and (S)-thalidomide was introduced as a sedative drug in the late 1950s. In 1961, it was withdrawn due to teratogenicity and neuropathy. There is now a growing clinical interest in thalidomide due to its unique anti-inflammatory and immunomodulatory effects.To critically review pharmacokinetic ...
T, Eriksson, S, Björkman, P, Höglund
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Clinical Pharmacology and Adolescence
Pediatric Clinics of North America, 1980When determining the type and timing of drug therapy for adolescents, certain biological and psychosocial factors unique to this age group must be considered. Modern drug monitoring techniques allow the physician to more successfully treat the adolescent patient.
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Clinical Pharmacology of Famotidine
Digestion, 2009The results of the initial clinical pharmacology studies of famotidine, a new H<sub>2</sub> receptor antagonist, are summarized. These studies indicate that: (1) single oral doses of famotidine (5–80 mg) were well tolerated; (2) famotidine effectively suppressed basal, nocturnal, pentagastrin- and meal-stimulated acid secretion; (3) the ...
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Clinical Pharmacology of Nicotine
Annual Review of Medicine, 1986Nicotine is the primary reason why people consume tobacco products and it may contribute to causation of tobacco-related diseases. This chapter reviews the human pharmacology of nicotine, the evidence for a role of nicotine in human disease, and the use of nicotine (gum) as a therapeutic agent in smoking cessation therapy.
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Clinical Pharmacology of Valpromide
Clinical Pharmacokinetics, 1991Valpromide has been used as an antiepileptic and antipsychotic drug for the past 25 years in several European countries. Unlike its corresponding acid, valproic acid, whose pharmacokinetics have been quite extensively reviewed, and despite years of clinical use, it appears that no reviews have been written on the pharmacokinetics of valpromide.
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Clinical pharmacology in Canada
Clinical Pharmacology & Therapeutics, 1974Information obtained from a poll of Canadian academic authorities concerning the extent of the need for and role to be served by clinical pharmacology is presented and discussed. Current problems are identified, the implications of the regulatory control of drug testing and marketing are explored, and recommendations for future action are outlined.
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