Results 31 to 40 of about 839,683 (307)

Clinical Pharmacology & Therapeutics: Past, Present, and Future. [PDF]

, 2017
Clinical Pharmacology & Therapeutics (CPT), the definitive and timely source for advances in human therapeutics, transcends the drug discovery, development, regulation, and utilization continuum to catalyze, evolve, and disseminate discipline ...
Terzic, Andre, Waldman, Scott A.
core   +2 more sources

The implementation of HTA in medicine pricing and reimbursement policies in Indonesia:Insights from multiple stakeholders [PDF]

, 2019
OBJECTIVES: This study aimed to identify the barriers and facilitators to improve the use of health technology assessment (HTA) for the selection of medicines listed in the e-Catalogue and the national formulary in Indonesia.
Afd Pharmacoepi & Clinical Pharmacology, Buskens, Erik, Feenstra, Talitha, Goettsch, Wim, Irawati, Sylvi, Makady, Amr, Pharmacoepidemiology and Clinical Pharmacology, Postma, Maarten, Wasir, Riswandy   +8 more
core   +2 more sources

2019 Overview [PDF]

, 2020
The CNS Neuroscience & Therapeutics provides a medium for rapid publication of original clinical, experimental, and translational research papers, timely reviews, and reports of novel findings of therapeutic relevance to the central nervous system.
Boltze, Johannes, Borlongan, Cesario, Dorandeu, Frederic, Giovanni, Giuseppe, Hu, Gang, Hu, Xiaoming, Lin, Jian‐Sheng, Luo, Yumin, Wu, Jie   +8 more
core   +1 more source

From multiscale biophysics to digital twins of tissues and organs: future opportunities for in silico pharmacology [PDF]

arXiv, 2023
With many advancements in in silico biology in recent years, the paramount challenge is to translate the accumulated knowledge into exciting industry partnerships and clinical applications. Achieving models that characterize the link of molecular interactions to the activity and structure of a whole organ are termed multiscale biophysics. Historically,
arxiv  

Pharmacology and clinical drug candidates in redox medicine [PDF]

, 2015
SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I, Cuadrado, Antonio, Dao, V Thao-Vi, Di Lisa, Fabio, Ghezzi, Pietro, Jaquet, Vincent, Kaludercic, Nina, Maghzal, Ghassan J, Robledinos-Anton, Natalia, Schmidt, Harald H H W, Seredenina, Tamara, Stocker, Roland   +11 more
core   +2 more sources

Impact of an integrative activity based on clinical practices on the teaching of basic and health care pharmacology curriculum to pharmacy students

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2021
Objective: The aim of this work was to evaluate the impact of an integrative activity based on clinical practices in disciplines of the basic and health care curriculum of an undergraduate pharmacy school.
Francisco A. FARIAS-FILHO, Lívia G. MADRUGA, Riethe O. ROCHA, Vinicius F. CARVALHO   +3 more
doaj   +1 more source

Integrating Expert ODEs into Neural ODEs: Pharmacology and Disease Progression [PDF]

arXiv, 2021
Modeling a system's temporal behaviour in reaction to external stimuli is a fundamental problem in many areas. Pure Machine Learning (ML) approaches often fail in the small sample regime and cannot provide actionable insights beyond predictions. A promising modification has been to incorporate expert domain knowledge into ML models.
arxiv  

Clinical Pharmacology of Antibody-Drug Conjugates

Antibodies, 2021
Antibody-drug conjugates (ADCs) are biopharmaceutical products where a monoclonal antibody is linked to a biologically active drug (a small molecule) forming a conjugate.
Iftekhar Mahmood
doaj   +1 more source

A pharmacokinetic -- viral kinetic model describes the effect of alisporivir monotherapy or in combination with peg-IFN on 2 hepatitis C virologic response [PDF]

Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2014, 96 (5), pp.599-608, 2015
Alisporivir is a cyclophilin inhibitor with demonstrated in vitro and in vivo activity against hepatitis C 11 virus (HCV). We estimated antiviral effectiveness of alisporivir alone or in combination with 12 pegylated-Inteferon (peg-IFN) in 88 patients infected with different HCV genotypes treated for four 13 weeks.
arxiv   +1 more source

Moxonidine: Pharmacology, Clinical Pharmacology and Clinical Profile

Blood Pressure, 1998
Management strategies in hypertension evolve in response to an increased understanding of underlying pathophysiological processes and developments and refinements in drug treatments. Recent research has identified the regulatory role of the imidazoline (I1) receptor in sympathetic outflow and blood pressure regulation and this has led to the ...
openaire   +3 more sources