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Introduction to dynamical systems analysis in quantitative systems pharmacology: basic concepts and applications [PDF]
, 2020 Quantitative systems pharmacology (QSP) can be regarded as a hybrid of pharmacometrics and systems biology. Here, we introduce the basic concepts related to dynamical systems theory that are fundamental to the analysis of systems biology models ...
채동우
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Good Research Practice in Non-Clinical Pharmacology and Biomedicine [PDF]
, 2020 This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical ...
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Pharmacological Research, 2023 Traditionally, clinical pharmacology has focused its activities on drug-organism interaction, from an individual or collective perspective. Drug efficacy assessment by performing randomized clinical trials and analysis of drug use in clinical practice by
Antonia Agustí +4 more
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Integrating pharmacology and clinical pharmacology [PDF]
British Journal of Clinical Pharmacology, 2011 I here reaffirm some of the points that I made in the manifesto for UK clinical pharmacology [1], in response to letters from others. Much of what I wrote in the manifesto addresses points that correspondents have made, but as some of the important points may not have been clear on a first reading, I shall reiterate them and add clarifications. I am
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Effectiveness of Revised Pharmacology Record Books as a Teaching-Learning Method for Second Year Medical Students [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: The goal of teaching medical undergraduates Pharmacology is to form a sound foundation of therapeutics. The pharmacology record books are maintained as a part of the curriculum.
Dhanya Sasidharan Palappallil +1 more
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Clinical Pharmacology of Sisomicin [PDF]
Antimicrobial Agents and Chemotherapy, 1975 Studies were conducted in 30 patients with neoplastic diseases. Twelve patients received sisomicin intramuscularly at doses of 20 mg/m 2 and 40 mg/m 2 . The mean peak serum concentration occurred at 1 h and was 2.5 μg/ml and 4.0 μg/ml, respectively. Ten patients received intravenous sisomicin
V, Rodriguez +3 more
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Saudi Pharmaceutical Journal, 2020 Drug development, from preclinical to clinical studies, is a lengthy and complex process. There is an increased interest in the Kingdom of Saudi Arabia (KSA) to promote innovation, research and local content including clinical trials (Phase I-IV ...
Abdullah Alsultan +7 more
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Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies [PDF]
, 2017 Objective: A novel tablet formulation containing an amorphous solid dispersion (ASD) of elacridar hydrochloride was developed with the purpose to resolve the drug’s low solubility in water and to conduct proof-of-concept clinical studies.
Schellens, J. H M +5 more
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Clinical Pharmacology of Antibody-Drug Conjugates
Antibodies, 2021 Antibody-drug conjugates (ADCs) are biopharmaceutical products where a monoclonal antibody is linked to a biologically active drug (a small molecule) forming a conjugate.
Iftekhar Mahmood
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Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? [PDF]
, 2020 As the field of artificial intelligence and machine learning (AI/ML) for drug discovery is rapidly advancing, we address the question "What is the impact of recent AI/ML trends in the area of Clinical Pharmacology?" We address difficulties and AI/ML ...
Zhavoronkov, Alex +8 more
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