Results 111 to 120 of about 1,094,070 (306)

Frontiers in Pharmacology

open access: yes
Frontiers in Pharmacology is a leading journal in its field, publishing rigorously peer-reviewed research across disciplines, including basic and clinical pharmacology, medicinal chemistry, pharmacy and toxicology.
letizia polito
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Clinical pharmacology in the UK, c. 1950–2000: industry and regulation [PDF]

open access: yes, 2008
Clinical pharmacology in the UK in the 1950s and 1960s was an exciting profession. Many important new drugs were developed and brought to market and a more systematic knowledge of drug effects in humans was needed, as well as ensuring the safety and ...

core  

Evaluation of in vitro Penetration of Fluticasone Propionate from MP-AzeFlu and Fluticasone Propionate Nasal Spray Through EpiAirway™606 Tissues Using Vertical Diffusion Cells

open access: yesJournal of Asthma and Allergy, 2020
William E Berger,1 Claus Bachert,2 Robert Allara,3 Arkady Koltun,4 Ferdinand Kopietz,5 Joachim G Maus,5 Alexander D D’Addio3 1Allergy and Asthma Associates of Southern California, Mission Viejo, CA, USA; 2Ghent University Hospital, Ghent, Belgium ...
Berger WE   +6 more
doaj  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Pharmacology of herbal remedies

open access: yes, 2016
Herbal Remedies used more frequently in the western society now a days. Chamomile mostly consumed as tea and the flower of the plant contains the vital component.
Bhatt, Kriya
core  

Neuroimmune Pharmacology: An Emerging Discipline for the Italian Society of Pharmacology

open access: yes, 2013
The present issue of the Journal of Neuroimmune Pharmacology (JNIP) contains abstracts for the Italian neuroimmune pharmacology (INIP) conference sponsored by SIF-Italian Society of Pharmacology ( http://www.sifweb.org/ ) scheduled for November 15th-16th
MARINO, FRANCA   +7 more
core   +1 more source

Frontiers in Pharmacology Experimental Pharmacology and Drug Discovery

open access: yes
Frontiers in Pharmacology is a leading journal in its field, publishing rigorously peer-reviewed research across disciplines, including basic and clinical pharmacology, medicinal chemistry, pharmacy and toxicology.
letizia polito
core   +1 more source

Effects of pharmacological and non‐pharmacological interventions

open access: yesThe Clinical Respiratory Journal, 2010
AbstractBackground:  Asthma is recognised as a condition with variable airway obstruction with pathophysiological features that include activation of a wide range of inflammatory and structural cells. Additionally, structural changes in the airways have been demonstrated. This includes increased thickening of components in the basement membrane region,
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

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