Results 91 to 100 of about 1,094,070 (306)
Update on Phytochemistry and Pharmacology of Naturally Occurring Resveratrol Oligomers
Molecules, 2017 Resveratrol oligomers (REVs), a major class of stilbenoids, are biosynthesized by regioselective oxidative coupling of two to eight units of resveratrol monomer.
Jie Shen +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Pharmacology of general anesthetics
, 2017 A detailed insight into the pharmacology of general anesthetics. Classification of general anesthetics, mode of action and an in depth review of both, volatile and intravenous anesthetics.általános orvosangolOrvosbiológia-farmakológiaegységes ...
Bhikha, Mehul Dinesh
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
ANNUAL SCIENTIFIC MEETING ON PHARMACOLOGY +ACY- THERAPY
, 2006 1+AC0-171 ...
+ADw-DEPARTMENT OF PHARMACOLOGY +ACY- THERAPEUTICS+AD4-
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Shenfu injection: a review of pharmacological effects on cardiovascular diseases
Frontiers in PharmacologyShenfu injection (SFI), composed of ginseng and aconite, is a Chinese patent developed from the classic traditional prescription Shenfu Decoction created more than 700 years ago.
Fei-Fei Xu +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Evaluation of teaching methods in pharmacology among MBBS students [PDF]
, 2017 Background: Pharmacology is one of the most important subjects in medical curriculum. It is basis of medical science and the foundation of treatment. The applied aspect forms the basis of clinical rational therapeutics.Methods: A cross-sectional study ...
Tushar R. Bagle +9 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source