Results 91 to 100 of about 1,473,821 (310)
Shenfu injection: a review of pharmacological effects on cardiovascular diseases
Frontiers in PharmacologyShenfu injection (SFI), composed of ginseng and aconite, is a Chinese patent developed from the classic traditional prescription Shenfu Decoction created more than 700 years ago.
Fei-Fei Xu +5 more
doaj +1 more source
Ingesting Magic: Ingredients and Ecstatic Outcomes in the Greek and Demotic Magical Papyri [PDF]
, 2017 There are spells in the Greek and Demotic Magical Papyri which promise divine visitations, assistants, ecstatic states, vessel inquiries, and vivid dreams. They also require powerful psychoactive botanical ingredients.
Sumler, Alan
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Clinical Pharmacology in the UK, c.1950-2000: Industry and Regulation [PDF]
, 2008 Annotated and edited transcript of a Witness Seminar held on 25 September 2007. Introduction by Professor Parveen Kumar, Barts and the London School of Medicine and Dentistry, University of London.First published by the Wellcome Trust Centre for the ...
Reynolds, LA, Tansey, EM
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Blood and Lymphatic Cancer: Targets and TherapyJianhua Chen,1,* Qing Liao,1,2,* Sha Yang,1 Jiaojiao Bian,1 Xianfu Li,3 Lu Zhao,4 Dan Wen,1 Dazhang Bai,5 Chunlei Yu,1 Chunyang Zhou,1 Zhengmin Xu1,6 1Department of Pharmacology Institute of Materia Medica, School of Pharmacy, North ...
Chen J +10 more
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Interaction between IP, TP, and 5-HT2 receptors during contractions to prostacyclin in rat renal arteries [PDF]
, 2015 Conference Theme: Tomorrow’s medicines: pharmacology, patients and populationspublished_or_final_versionConference Theme: Tomorrow's medicines: pharmacology, patients and ...
Baretella, OM, Vanhoutte, PMGR, Xu, A
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Editorial: New trends in natural product research for inflammatory and infectious diseases
Frontiers in Pharmacology, 2022 Jaime Ribeiro-Filho +3 more
doaj +1 more source