Results 81 to 90 of about 1,024,322 (315)

Evaluation of Chitosan–Pimelate Buccal Film Loaded with Duloxetine-Modified Sage Lipid Carriers Nanoformulation for Effective Antidepressant Activity in a Rat Model

International Journal of Nanomedicine
Walaa A El-Dakroury,1 Yousra A Nomier,2 Abdelrahman R Said,1 Magaji Garba Taura,3 Ahmed Soliman Doghish,4,5 Asem Shalaby,6 Omnia M Sarhan1 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr ...
El-Dakroury WA, Nomier YA, Said AR, Taura MG, Soliman Doghish A, Shalaby A, Sarhan OM   +6 more
doaj  

Pharmacology treatment of Malaria

, 2017
For decades, malaria has been known to be a lethal disease which can be transmitted quickly via the mosquito vector and cause outbreaks in many areas in the world.
Tran, Nguyen Thuc Anh
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

ANNUAL SCIENTIFIC MEETING ON PHARMACOLOGY +ACY- THERAPY

, 2006
1+AC0-171 ...
+ADw-DEPARTMENT OF PHARMACOLOGY +ACY- THERAPEUTICS+AD4-
core  

Neuroimmune Pharmacology: An Emerging Discipline for the Italian Society of Pharmacology

, 2013
The present issue of the Journal of Neuroimmune Pharmacology (JNIP) contains abstracts for the Italian neuroimmune pharmacology (INIP) conference sponsored by SIF-Italian Society of Pharmacology ( http://www.sifweb.org/ ) scheduled for November 15th-16th
MARINO, FRANCA, S. Cuzzocrea, F. Marino, Monica Luca, M. Di Luca, COSENTINO, MARCO, Salvatore Cuzzocrea, M. Cosentino   +7 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Update on Phytochemistry and Pharmacology of Naturally Occurring Resveratrol Oligomers

Molecules, 2017
Resveratrol oligomers (REVs), a major class of stilbenoids, are biosynthesized by regioselective oxidative coupling of two to eight units of resveratrol monomer.
Jie Shen, Qiang Zhou, Pei Li, Zhiqiang Wang, Shuangshuang Liu, Chunnian He, Chunhong Zhang, Peigen Xiao   +7 more
doaj   +1 more source

Pharmacology of general anesthetics

, 2017
A detailed insight into the pharmacology of general anesthetics. Classification of general anesthetics, mode of action and an in depth review of both, volatile and intravenous anesthetics.általános orvosangolOrvosbiológia-farmakológiaegységes ...
Bhikha, Mehul Dinesh
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source