Results 71 to 80 of about 1,473,821 (310)
A Comprehensive Review of the Phytochemistry and Therapeutic Efficacy of Viola yedoensis Makino
MoleculesViola yedoensis Makino (V. yedoensis), a perennial herb in the Violaceae family, is recognized for its violet flowers and has a longstanding role in ethnomedicine for treating various inflammatory diseases, such as boils, furuncles, carbuncles, and both ...
Shuang Wang +5 more
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Frontiers in Integrative Neuroscience, 2018 Motor sequence learning, planning and execution of goal-directed behaviors, and decision making rely on accurate time estimation and production of durations in the seconds-to-minutes range. The pathways involved in planning and execution of goal-directed
Catalin V. Buhusi +6 more
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Ballota nigra L. – an overview of pharmacological effects and traditional uses
Herba Polonica, 2020 Ballota nigra, also known as black horehound is a common medical herb used in folk medicine around the world. First reported mentions of its medical properties and use goes as far as the 13th century.
Przerwa Filip +2 more
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Studies of the physiology, pharmacology, and biochemistry of the auxins [PDF]
, 1952 Several excellent reviews of auxin matters have appeared during the past few years dealing broadly with the subject as a whole, such as the Wisconsin Symposium on Plant Growth Substances whleh is referred to repeatedly below, as well as reviews of more ...
Bandurski, Robert S., Bonner, James
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
European Journal of Medical Research, 2011 Echinocandins represent the newest class of antifungal agents. Currently, three echinocandins, anidulafungin, caspofungin and micafungin are licensed for clinical use in various indications.
Kofla G, Ruhnke M
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ATP as a presynaptic modulator [PDF]
, 2000 © 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy,
Cunha, Rodrigo A., Ribeiro, J. A.
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Clinical Case Reports, 2019 Our rechallenge of cobimetinib in an Erdheim‐Chester Disease (ECD) patient for the rare adverse effect, “dropped head syndrome,” with a previously unexplored cobimetinib regimen was successful.
Amber C. King +6 more
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