Advanced Functional Materials, EarlyView.The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar +6 more
wiley +1 more source
The Impact of QSP Modeling on the Design and Optimization of Gene Therapy Approaches. [PDF]
CPT Pharmacometrics Syst PharmacolRayad N, Chowdhury EA, Meno-Tetang GML.
europepmc +1 more source
Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Correction: Integrating network pharmacology and transcriptomics to identify solasonine's anti-osteosarcoma targets and experimental validation. [PDF]
Front OncolWei D, Li M, Chu D, Shi J.
europepmc +1 more source
Advanced Functional Materials, EarlyView.Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li +11 more
wiley +1 more source
RETRACTION: Systems Pharmacology Reveals the Mechanism of Activity of Physalis alkekengi L. var. Franchetii Against Lipopolysaccharide-Induced Acute Lung Injury. [PDF]
J Cell Mol Medeuropepmc +1 more source
Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants
Advanced Functional Materials, EarlyView.Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño +5 more
wiley +1 more source
Correction: Correlation analysis between plasma concentration of nilotinib and clinical efficacy and safety in patients with chronic myeloid leukemia: a single-center retrospective cohort study. [PDF]
Front PharmacolLiu Y, Lin T, Zhao B, Li Y, Zheng P.
europepmc +1 more source
Menthol: A Comprehensive Review of Its Pharmacological Properties and Therapeutic Applications
K. Hüsnü Can Başer +2 more
openalex +1 more source