Results 11 to 20 of about 213,112 (50)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundHeterozygous loss of function mutations in the KCNK3 gene cause hereditary pulmonary arterial hypertension (PAH). KCNK3 encodes an acid‐sensitive potassium channel, which contributes to the resting potential of human pulmonary artery smooth ...
Michael S. Bohnen +6 more
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To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?
Frontiers in Pharmacology, 2020 The family of ligand-gated ion channels known as P2X receptors were discovered several decades ago. Since the cloning of the seven P2X receptors (P2X1-P2X7), a huge research effort has elucidated their roles in regulating a range of physiological and ...
Leanne Stokes +3 more
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Curcumin: Total-Scale Analysis of the Scientific Literature
Molecules, 2019 The current study aimed to provide a comprehensive bibliometric overview of the literature on curcumin, complementing the previous reviews and meta-analyses on its potential health benefits.
Andy Wai Kan Yeung +15 more
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Exploring the Pharmacological Potential of Metformin for Neurodegenerative Diseases
Frontiers in Aging Neuroscience, 2022 Metformin, one of the first-line of hypoglycemic drugs, has cardioprotective, anti-inflammatory and anticancer activities, in addition to its proven hypoglycemic effects.
Ming-Rui Du +5 more
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Molecules, 2015 Varied pharmacological responses have been reported for mitragynine in the literature, but no supportive scientific explanations have been given for this.
Surash Ramanathan +5 more
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Frontiers in Pediatrics, 2022 Bronchopulmonary dysplasia (BPD) is one of the most common health complications of premature birth. Corticosteroids are commonly used for treatment of BPD, but their use is challenging due to variability in treatment response.
Bradley Stockard +4 more
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Frontiers in Computational Neuroscience, 2018 The parieto-occipital alpha (8–13 Hz) rhythm is by far the strongest spectral fingerprint in the human brain. Almost 90 years later, its physiological origin is still far from clear.
Diego Lozano-Soldevilla
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Tocolysis effects of traditional Chinese medicine and their effective components
World Journal of Traditional Chinese Medicine, 2022 Traditional Chinese medicine (TCM) for anti-abortion is based on the theory of gynecology of TCM, which aims to prevent and treat abdominal pain during pregnancy, fetal leakage, uneasy fetal movement, and fetal atrophy.
Tong-Hua Zhang +8 more
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Toxicity and Anti-promastigote Activity of Benzoxazinoid Analogs Against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: Here, we aim to evaluate the antileishmanial activity of compounds with a benzoxazinoid (BX) skeleton, previously synthesized by our group, against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum promastigotes.
Gilberto de Sousa +7 more
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MAMC Journal of Medical Sciences, 2022 Objectives: Assessment of student’s learning outcomes in alignment with the teaching goals can be a tool for modification of curriculum and teaching methods.
Syed Shariq Naeem, Vandana Roy
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