Results 11 to 20 of about 1,002,895 (267)

Cannabis: a multifaceted plant with endless potentials

Frontiers in Pharmacology, 2023
Cannabis sativa, also known as “hemp” or “weed,” is a versatile plant with various uses in medicine, agriculture, food, and cosmetics. This review attempts to evaluate the available literature on the ecology, chemical composition, phytochemistry ...
Eric Fordjour, Eric Fordjour, Charles F. Manful, Albert A. Sey, Rabia Javed, Thu Huong Pham, Raymond Thomas, Mumtaz Cheema   +7 more
doaj   +1 more source

Anemia from A to zinc: Hypocupremia in the setting of gastric bypass and zinc excess

Clinical Case Reports, 2020
Hypocupremia can result in a bi‐lineage deficiency of leukocytes and erythrocytes. Although commonly seen from gastrointestinal malabsorption, hypocupremia can be further exacerbated with excessive zinc intake causing increased fecal copper excretion ...
Vineeth Tatineni, Julie Y. An, Matthew R. Leffew, Sameer A. Mahesh   +3 more
doaj   +1 more source

The Potential of Parsley Polyphenols and Their Antioxidant Capacity to Help in the Treatment of Depression and Anxiety: An In Vivo Subacute Study

Molecules, 2021
Depression and anxiety are major mental health problems in all parts of the world. These illnesses are associated with a number of risk factors, including oxidative stress.
Imane Es-safi, Hamza Mechchate, Amal Amaghnouje, Omkulthom Mohamed Al Kamaly, Fatima Zahra Jawhari, Hamada Imtara, Andriy Grafov, Dalila Bousta   +7 more
doaj   +1 more source

Using the TI.VA algorithm to titrate the depth of general anaesthesia: a first-in-humans study

BJA Open, 2023
Background: The dose of anaesthetic and opioid drugs must be continuously adjusted after the induction of general anaesthesia to maintain an adequate depth of anaesthesia.
Emiliano Tognoli, Mariani Luigi
doaj   +1 more source

ARE ALL THE PROLONGED DRUG FORMULATIONS OF NIFEDIPINE THE SAME?

Рациональная фармакотерапия в кардиологии, 2016
Publication is devoted to the calcium antagonist nifedipine in drug formulations of the prolonged action. Comparison of technological peculiarities of these formulations is given, pharmacokinetic and pharmacodynamic effects are reviewed.
V. G. Kukes, D. A. Sychev
doaj   +1 more source

Pleurostylia capensis Turcz (Loes): A review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses

Journal of Medicinal Plants for Economic Development, 2023
Background: Pleurostylia capensis Turcz (Loes) is a tree species found in Africa that has been used in traditional medicine for various ailments. Aim: This review aims to investigate the phytochemistry, pharmacology and toxicity of P.
Nokukhanya E. Thembane
doaj   +1 more source

Análisis del conocimiento sobre la administración de fármacos

European Journal of Investigation in Health, Psychology and Education, 2015
El objetivo de este estudio fue conocer el conocimiento de los profesionales sanitarios del Hospital de Montilla sobre la administración de medicamentos en urgencias. Material: estudio descriptivo de corte transversal realizado en el Hospital de Montilla
Juan Manuel Carmona Torres, Ana María Baena Serrano, Ana Cristina Berral Jiménez, Quintiliano Sotelo Baena, Beatriz Recio Andrade, Irene Recio Andrade   +5 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Traditional uses, phytochemistry, pharmacology and toxicology of garlic (Allium sativum), a storehouse of diverse phytochemicals: A review of research from the last decade focusing on health and nutritional implications

Frontiers in Nutrition, 2022
Allium sativum L. (Garlic) is a fragrant herb and tuber-derived spice that is one of the most sought-after botanicals, used as a culinary and ethnomedicine for a variety of diseases around the world.
Champa Keeya Tudu, Tusheema Dutta, Mimosa Ghorai, Protha Biswas, Dipu Samanta, Patrik Oleksak, Niraj Kumar Jha, Niraj Kumar Jha, Niraj Kumar Jha, Manoj Kumar, Radha, Jarosław Proćków, José M. Pérez de la Lastra, Abhijit Dey   +13 more
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source