β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Correction to "The <i>In Vitro</i> Effect of Psoralen on Glioma Based on Network Pharmacology and Potential Target Research". [PDF]
europepmc +1 more source
Correction: Anticancer effects of OSW-1 on glioma cells <i>via</i> regulation of the PI3K/AKT signal pathway: a network pharmacology approach and experimental validation <i>in vitro</i> and <i>in vivo</i>. [PDF]
Zhan Z +6 more
europepmc +1 more source
Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello +5 more
wiley +1 more source
Editorial: Genomic discoveries and pharmaceutical development in urologic tumors - volume II. [PDF]
Li W, Meng J, Yang H, Zhang T, Yin L.
europepmc +1 more source
Phytochemical and pharmacological screening of Sargassium vulgare from Suez Canal, Egypt
Mohamed A. Shreadah +3 more
openalex +2 more sources
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
Retraction Note: The antihypertensive effect of the coadministration of exercise and eugenol in deoxycorticosterone acetate-induced hypertension in rats. [PDF]
Abdallah MA +4 more
europepmc +1 more source

