Results 21 to 30 of about 573,768 (206)
Mitochondrial pharmacology [PDF]
Trends in Pharmacological Sciences, 2012 Mitochondria are being recognized as key factors in many unexpected areas of biomedical science. In addition to their well-known roles in oxidative phosphorylation and metabolism, it is now clear that mitochondria are also central to cell death, neoplasia, cell differentiation, the innate immune system, oxygen and hypoxia sensing, and calcium ...
Smith, R.A.J. +3 more
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
English Language Acculturation and Academic Achievement Among Junior Year Nursing Students [PDF]
, 2009 Efforts to alleviate the current nursing shortage have focused on recruitment and retention of diverse nursing students. Language acculturation has been identified in the literature as one predictor of academic achievement (Salamonson et al, 2008 ...
Lukrich, Leah
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FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
, 2011 The popular trope which depicts the origin of life on earth as emerging from a ?chemical soup? continues to have an enduring hold over the imagination. Of course, whether this ?soup?
Boothroyd, Dave
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Tourette syndrome research highlights 2015 [version 1; referees: 3 approved] [PDF]
, 2016 We present selected highlights from research that appeared during 2015 on Tourette syndrome and other tic disorders. Topics include phenomenology, comorbidities, developmental course, genetics, animal models, neuroimaging, electrophysiology, pharmacology,
Black, Kevin J, Richards, Cheryl A
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BioMed Research International, 2014 ispartof: location:United ...
Allegaert Karel +3 more
openaire +4 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
A Multi-Level Analysis of World Scientific Output in Pharmacology [PDF]
, 2012 The purpose of this chapter is to analyse international research in “pharmacology, toxicology and pharmaceutics” (hereafter pharmacology) on the basis of the scientific papers listed in the Scopus multidisciplinary database.
Olmeda-Gómez, Carlos +2 more
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