Results 151 to 160 of about 178,669 (290)
National-, institutional-, and individual-level determinants of pharmacology and pharmacy research excellence: an analysis of stanford-elsevier lists of the top 2% scholars (2017-2023). [PDF]
Riad A +3 more
europepmc +1 more source
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen +7 more
wiley +1 more source
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun +15 more
wiley +1 more source
The Journal of Pharmacy and Pharmacology 2008
openaire +2 more sources
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan +10 more
wiley +1 more source
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
Enhancing pharmacology learning through student-led presentations: A qualitative descriptive cross-sectional thematic analysis of pharmacy students' perceptions. [PDF]
Almalki MA +4 more
europepmc +1 more source
The Journal of Pharmacy and Pharmacology 2013
openaire +2 more sources
Supplying emergency contraception pills through community pharmacies without the need for a doctor's prescription is an important public health role for the pharmacy staff, as a way of reducing unwanted pregnancies and induced abortions.
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