Results 41 to 50 of about 169,938 (297)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Pharmacy Matters - March 2019 [PDF]

, 2019
Featured stories: CEO off Clinical Pharmacy Organization Delivers Hartman Lecture, Pharmacy Faculty Honored with ASHP Distinguished Service Awards, Pharmacology Professor Awarded NIA Grant for Research on Aging Brain, Pharmacy Faculty Members ...
University of Mississippi. School of Pharmacy
core   +1 more source

A Multi-Level Analysis of World Scientific Output in Pharmacology [PDF]

, 2012
The purpose of this chapter is to analyse international research in “pharmacology, toxicology and pharmaceutics” (hereafter pharmacology) on the basis of the scientific papers listed in the Scopus multidisciplinary database.
Antonio Perianes-Rodríguez, Ovalle-Perandones, María-Antonia, Perianes-Rodríguez, Antonio, Olmeda-Gómez, Carlos, Carlos Olmeda-Gmez, Antonio Perianes-Rodrguez, Ovalle-Perandones, María Antonia, Carlos Olmeda-Gómez, Ma-Antonia Ovalle-Perandones   +8 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

College of Pharmacy Bulletin - 1976 [PDF]

, 1976
General program information concerning the University of Utah College of Pharmacy on admission, curriculum requirements, courses of instruction, electives, special programs, and licensure.College of Pharmacy - Pharmacy at the University of Utah ...

core  

TRADITIONS OF SIENTIFIC SCHOOLS IN THE HISTORY OF SCIENCE DEPARTMENT OF PHARMACOLOGY OF PHARMACEUTICAL FACULTY OF THE I.M. SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY

Сеченовский вестник, 2013
The chair of pharmacology, faculty of pharmacy of the I.M. Sechenov First MSMU formed the Moscow school of teaching pharmacology at the Institute of Pharmacy and Pharmaceutical Institute, is a prestigious scientific pharmaceutical center.
A. A. Svistunov, N. P. Bykov
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Projecting the future size of the Lebanese pharmacy workforce: forecasts until the year 2050 [PDF]

, 2019
Background: Despite the rigorous regulations governing the pharmacy profession in Lebanon, the increasing numbers of pharmacy graduates seem to be the greatest threat of demise.
Hajj, Aline, Salameh, Pascale R., Zeenny, Rony M., Sacre, Hala, Sili, Georges, Hallit, Souheil R.   +5 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

College of Pharmacy Bulletin - 1975 [PDF]

, 1975
General program information concerning the University of Utah College of Pharmacy on admission, curriculum requirements, courses of instruction, electives, special programs, and licensure.College of Pharmacy - Pharmacy at the University of Utah ...

core