Results 11 to 20 of about 32,420 (200)

Separation and Identification of Impurity of Chlortetracycline Hydrochloride Not Included in the European Pharmacopoeia. [PDF]

Biomed Chromatogr
ABSTRACT Drug impurities can affect the clinical efficacy of medicines and may even present substantial health risks. Consequently, the regulation and investigation of such impurities are critically important. In this study, we observed that the chemical structure of impurity E in chlortetracycline hydrochloride, as described in the European ...
Chen X, Meng J.
europepmc   +2 more sources

Phytochemical Analysis of Veratrum Alkaloids in Medicinal Veratrum Globules Using High-Performance Liquid Chromatography Coupled With Tandem Mass Spectrometry. [PDF]

Biomed Chromatogr
ABSTRACT Veratrum L. species have been used in traditional medicine for centuries due to their bioactive properties, yet they also contain toxic steroid alkaloids that pose potential health risks when present in herbal preparations. Reliable analytical approaches are therefore essential to ensure product safety, protect consumer health and assess ...
Siegle J, Pietsch J.
europepmc   +2 more sources

The Comparative Study of Different Pharmacopoeias: Indian Pharmacopoeia, British Pharmacopoeia, United States Pharmacopoeia

Open Access Journal of Pharmaceutical Research, 2023
The objective of the study is to ensure Indian pharmacopoeia monographs are on par with United States, British pharmacopoeia standards. A few monographs were selected on random and compared. It has been observed that Indian pharmacopoeia has replaced titrimetrry assay method of analysis to sophisticated chromatographic techniques.
openaire   +1 more source

Development and validation of microbial bioassay for quantification of Levofloxacin in pharmaceutical preparations

Journal of Pharmaceutical Analysis, 2015
The aim of this study was to develop and validate a simple, sensitive, precise and cost-effective one-level agar diffusion (5+1) bioassay for estimation of potency and bioactivity of Levofloxacin in pharmaceutical preparation which has not yet been ...
Nishant A. Dafale, Uttam P. Semwal, Piyush K. Agarwal, Pradeep Sharma, G.N. Singh   +4 more
doaj   +1 more source

Safety monitoring of orthopaedic implants under the Materiovigilance programme of India – A current perspective

Journal of Orthopaedic Reports, 2023
Introduction: The safety of medical devices, used in orthopaedics is monitored under the Materiovgilance Programme of India (MvPI). Methods: This article aims to convey the process of Orthopaedic implants (OIs) associated adverse events (AE) reporting to
Kalaiselvan V, Shubhang Arora, Rajeev Singh Raghuvanshi   +2 more
doaj   +1 more source

Pharmacognostical studies of Ricinus communis under the influence of industrial effluent

The Indian Journal of Agricultural Sciences, 2015
The aim of the present study is to evaluate the pharmacognostical markers of Ricinus communis L., an attempt has been made for a comparative study of plants growing near the vicinity of polluted, Atlas Cycles Industry, with those plants growing in non ...
KAVITA TYAGI, RAJAT RASHMI, SHAHIDUL KHAIR   +2 more
doaj   +1 more source

Preliminary studies of acute and sub-chronic toxicity of the aqueous extract of Guibourtia tessmannii (Harms) J. Leonard stem barks (Caesalpiniaceae) in mice and rats

Asian Pacific Journal of Tropical Biomedicine, 2016
Objective: To investigate the toxicity of aqueous extract of Guibourtia tessmannii (Harms) J. Leonard (G. tessmannii) and evaluate its safety. Methods: NMRI mice were used to determine the acute toxicity of G. tessmannii. Increasing concentrations of the
Noreen Orianna Koumba Madingou, Aristide Traore, Alain Souza, Marlaine Michelle Boukandou Mounanga, Raissa Reine Aworet Samseny, Sylvin Ouedraogo, Alfred Sababenedyo Traore   +6 more
doaj   +1 more source

Analysis of the provisions of national and EAEU legislation regulating pharmaceuticals before and after 1 January 2026

Регуляторные исследования и экспертиза лекарственных средств, 2023
Scientific relevance. The gradual transition to the common pharmaceutical market within the Eurasian Economic Union (EAEU) is expected to be completed by the end of 2025, and a new regulatory framework is currently being developed at both the national ...
A. G. Zaremba, E. M. Rychikhina
doaj   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Impacts of SAYE PLUS, an Antimalarial Phytomedicine With Potential Anti-COVID-19, on the Physical, Biological, and Genotoxicity Parameters of Rodents in Short-Term Toxicity Studies

Journal of Toxicology
In response to the COVID-19 pandemic and following the World Health Organization’s call for action, several traditional medicine recipes were used without any scientific prerequisites concerning their safety.
Joël Ouédraogo, Sylvain Ilboudo, Geoffroy Gueswindé Ouédraogo, Virginie Dakuyo, Salfo Ouédraogo, Gaétan D. Somda, Jean Claude Romaric Pingdwindé Ouédraogo, Moussa Ouédraogo, Rasmané Semdé, Sylvin Ouédraogo   +9 more
doaj   +1 more source