Results 51 to 60 of about 74,267 (242)

Five‐Grass‐Pollen Sublingual Immunotherapy Drops Are Efficacious and Well Tolerated in Adults: The RHAPSODY Phase III Trial

Allergy, EarlyView.
The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier, Ruta Gronskyte Juhl, Terrie Dalgaard, Antoine Chartier, Philippe Devillier   +4 more
wiley   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo, Sepideh Mehravar, Ellen Choi, Ju Dong Yang, Hyun‐Seok Kim, Yun Wang, Aarshi Vipani, Hirsh D. Trivedi, Walid Ayoub, Parnian Naji, Alexander Kuo, Chun‐Ying Wu, Lorenzo Leggio, Juan Pablo Arab   +13 more
wiley   +1 more source

Could Pharmacopoeial Reference Standards Serve as a Platform to Enhance the Quality and Safety Control Systems of European Food Supplement Businesses?

European Journal of Risk Regulation
Previous research has highlighted several quality-related concerns regarding food supplements available on the market, which compromise their safe consumption. This study evaluates whether the adoption of the European Pharmacopoeia (Ph.
Roman Warda, Kai Purnhagen, Milica Molitorisová   +2 more
doaj   +1 more source

Medicinal plants of the Chinese Pharmacopoeia and Daodi: insights from phylogeny and biogeography [PDF]

, 2018
The Chinese Pharmacopoeia 2015 includes 584 plant medicines, of which 284 also contain high quality subsets, so called ‘Daodi’ components, where Daodi denotes superior clinical properties compared to non-Daodi counterparts despite being sourced from the ...
Al-Adhroey, Balick, Beckwith, Bennett, Bertea, Browner, Fu, Gorji, Heinrich, Hu, Hu, Huang, Huang, Jamal, Kala, Kishore, Leon, Leonti, Letunic, Meng, Moerman, Moerman, Ouarghidi, Pan, Qian, Qian, Revell, Saslis-Lagoudakis, Saslis-Lagoudakis, Saslis-Lagoudakis, Shrestha, Sivasankari, Stein, Tan, Tan, Uniyal, van Andel, Weber, Xing, Xue, Zhang, Zhao   +41 more
core   +1 more source

Pharmacopoeia: Illness narratives [PDF]

British Journal of Clinical Pharmacology, 2021
Liz Lee, Susie Freeman
openaire   +2 more sources

Human Pancreatic Cancer Organoids

Cell Proliferation, EarlyView.
This guideline establishes a comprehensive framework for the application of patient‐derived pancreatic cancer organoids. It outlines the stringent technical requirements and testing methods necessary to ensure high fidelity to the original tumor tissue, including morphological assessment, pathological biomarker expression (e.g., CK19, CK7), and genetic
Aina He, Xiaolin Lin, Xiaozhe Qian, Jiasheng Mu, Zhonghua Tao, Jin Gu, Yonggang Wang, Ting Han, Hongling Zhao, Yalong Wang, Jian Zhang, Zunqiang Zhou, Ligang Xing, Changchun Zhou, Dongyuan Zhu, Zengjun Liu, Gang Chen, Qinghe Zhou, Xiaoguang Wang, Shasha Zhao, Xiao Liu, Dongyan Cao, Bin Yu, Zebing Liu, Jiabei Wang, Gengming Niu, Guiying Wei, Maorong Chen, Weiping Wang, Xiaonan Kang, Junmei Zhou, Shuai Gong, Ying Xie, Jianming Zhang, Xianming Kong, Chunyan Dong, Yanmei Zou, Lina Tang, Aijin Ma, Hua Xiong, Xuemei Liu, Tongbiao Zhao, Jie Hao, Xiuying Xiao, Dongxi Xiang   +44 more
wiley   +1 more source

Phylogenomic Approaches to DNA Barcoding of Herbal Medicines: Developing Clade-Specific Diagnostic Characters for Berberis

Frontiers in Plant Science, 2019
DNA barcoding of herbal medicines has been mainly concerned with authentication of products in trade and has raised awareness of species substitution and adulteration.
Marco Kreuzer, Caroline Howard, Bhaskar Adhikari, Colin A. Pendry, Julie A. Hawkins   +4 more
doaj   +1 more source

Prevention of endotoxin-induced uveitis in rabbits by Triphala, an Ayurvedic formulation [PDF]

, 2011
Purpose: Triphala (TA) is an Ayurvedic formulation used to treat various disorders. The present study was designed to investigate the anti-inflammatory effect of TA aqueous extract on experimental uveitis in the rabbit.
Suresh Kumar Gupta, V. Kalaiselvan, Shyam Sunder Agrawal, Sushma Srivastava, Rohit Saxena, Int J Cur Biomed Phar Res.
core  

Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets [PDF]

, 2020
Background:Dissolution of artemether (ART ) and lumefantrine (LUM) active pharmaceutical ingredients (APIs) in fixed dose combination (FDC) ART/LUM tablets is one of the critical quality attributes.
De Spiegeleer, Bart, Duchateau, Luc, Duguma, Markos, Suleman, Sultan, Teshome, Henok, Wynendaele, Evelien, Yohannes, Sileshi Belew   +6 more
core   +1 more source

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, EarlyView.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher   +2 more
wiley   +1 more source